Cognition and the five-factor model of the Positive and Negative Syndrome Scale in schizophrenia
Cognition and the five-factor model of the Positive and Negative Syndrome Scale in schizophrenia
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DOI：
10.1016/j.schres.2012.10.020
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发表时间：
2013-01-01
影响因子：
4.5
通讯作者：
Palomo, Tomas
中科院分区：
文献类型：
--
作者：
Rodriguez-Jimenez, Roberto;Bagney, Alexandra;Palomo, Tomas
阳性和阴性症状量表（PANSS）的不同探索性和验证性因子分析发现了许多因素，而不是原来的阳性，阴性和一般的精神病理学。基于对先前研究的回顾并使用验证性因素分析（CFA），Wallwork等人（Schizophr Res 2012; 137：246-250）最近提出了PANSS的共识五因素结构。这个解决方案包括一个认知因素，这可能是一个有用的措施，认知精神分裂症。我们的目的是1）研究PANSS共识五因素模型的心理测量学特性（因素结构和信度）; 2）研究使用威斯康星州卡片分类测验（WCST）评估的执行绩效与拟议的PANSS共识认知因素（由项目P2-N5-G11组成）之间的关系。这项横断面研究包括201名西班牙门诊诊断为精神分裂症的最终样本。对于我们的第一个目标，CFA进行Cronbach的α的五个因素进行了计算，第二个目标，序贯线性回归分析。验证性因素分析的拟合指数为NNFI=0.94，CFI=0.95，RMSEA=0.08。五个因素的Cronbach’s α值是足够的。回归分析表明，PANSS的五因素模型比经典的三因素模型更能解释WCST的方差。此外，较高的认知因子得分与WCST表现较差相关。这些结果支持其因子结构和可靠性提供了鲁棒性的共识PANSS五因素模型，并表明一些有用的认知因素在精神分裂症患者的临床评估。(C)2012爱思唯尔有限公司版权所有。
Different exploratory and confirmatory factorial analyses of the Positive and Negative Syndrome Scale (PANSS) have found a number of factors other than the original positive, negative, and general psychopathology. Based on a review of previous studies and using confirmatory factor analyses (CFA), Wallwork et al. (Schizophr Res 2012; 137: 246-250) have recently proposed a consensus five-factor structure of the PANSS. This solution includes a cognitive factor which could be a useful measure of cognition in schizophrenia. Our objectives were 1) to study the psychometric properties (factorial structure and reliability) of this consensus five-factor model of the PANSS, and 2) to study the relationship between executive performance assessed using the Wisconsin Card Sorting Test (WCST) and the proposed PANSS consensus cognitive factor (composed by items P2-N5-G11). This cross-sectional study included a final sample of 201 Spanish outpatients diagnosed with schizophrenia. For our first objective, CFA was performed and Cronbach's alphas of the five factors were calculated; for the second objective, sequential linear regression analyses were used. The results of the CFA showed acceptable fit indices (NNFI=0.94, CFI=0.95, RMSEA=0.08). Cronbach's alphas of the five factors were adequate. Regression analyses showed that this five-factor model of the PANSS explained more of the WCST variance than the classical three-factor model. Moreover, higher cognitive factor scores were associated with worse WCST performance. These results supporting its factorial structure and reliability provide robustness to this consensus PANSS five-factor model, and indicate some usefulness of the cognitive factor in the clinical assessment of schizophrenic patients. (C) 2012 Elsevier B.V. All rights reserved.