Measurement and calculation of characteristic prompt gamma ray spectra emitted during proton irradiation
Measurement and calculation of characteristic prompt gamma ray spectra emitted during proton irradiation
复制标题
DOI：
10.1088/0031-9155/54/22/n02
复制
发表时间：
2009-11-21
影响因子：
3.5
通讯作者：
Trache, L.
中科院分区：
文献类型：
--
作者：
Polf, J. C.;Peterson, S.;Trache, L.
在本文中，我们提出了在质子束照射期间从组织等效体模发出的瞬发伽马射线谱（由质子-核相互作用产生）的初始测量和计算结果。使用铅屏蔽（被动屏蔽）或康普顿抑制系统（主动屏蔽）的高纯度锗探测器进行瞬发伽马射线光谱的测量。使用 Geant4 蒙特卡罗工具包开发的无源和有源屏蔽实验装置模型进行光谱计算。从测量的光谱中可以看出，在传递与患者治疗期间传递的质子剂量类似的质子剂量期间，可以将特征发射线与受照射模型中的主要元素组成原子（C、O、Ca）区分开来。此外，蒙特卡罗光谱被发现与测量的光谱非常一致，为我们的模型提供了初步验证，以用于质子治疗期间瞬发伽马射线发射的进一步研究。
In this paper, we present results of initial measurements and calculations of prompt gamma ray spectra (produced by proton-nucleus interactions) emitted from tissue equivalent phantoms during irradiations with proton beams. Measurements of prompt gamma ray spectra were made using a high-purity germanium detector shielded either with lead (passive shielding), or a Compton suppression system (active shielding). Calculations of the spectra were performed using a model of both the passive and active shielding experimental setups developed using the Geant4 Monte Carlo toolkit. From the measured spectra it was shown that it is possible to distinguish the characteristic emission lines from the major elemental constituent atoms (C, O, Ca) in the irradiated phantoms during delivery of proton doses similar to those delivered during patient treatment. Also, the Monte Carlo spectra were found to be in very good agreement with the measured spectra providing an initial validation of our model for use in further studies of prompt gamma ray emission during proton therapy.