Neurohormonal Regulation of Appetite and its Relationship with Stress: A Mini Literature Review.
Neurohormonal Regulation of Appetite and its Relationship with Stress: A Mini Literature Review.
复制标题
DOI：
10.7759/cureus.3032
复制
发表时间：
2018-07-23
期刊：
影响因子：
--
通讯作者：
Shrestha B
中科院分区：
文献类型：
--
作者：
Ans AH;Anjum I;Satija V;Inayat A;Asghar Z;Akram I;Shrestha B
长期以来，人们都知道压力会影响人类的饮食行为。应激诱导的摄食过多被认为是肥胖症发展的潜在原因。鉴于肥胖症的高患病率及其与其他心血管和代谢疾病的关联，压力诱导的饮食问题变得更加重要。我们回顾了过去的研究数据，以进一步阐明人类压力，食欲调节和饮食模式之间的关系。尽管很难肯定地说一个人暴露在压力下会吃得太少或太多，但可以做出某些假设。一般来说，急性压力会导致进食减少，而慢性压力会导致进食增加。糖皮质激素，应激反应的效应分子，增加了消耗高热量，可口食物的倾向。进一步的研究可以将应激反应的生物标志物与食欲调节的激素和神经递质联系起来，这可以拓宽我们对这一主题的理解。这些研究可以为制定有效的抗肥胖策略提供基础。
Stress has long been known to affect eating behaviors in humans. Stress-induced hyperphagia is considered a potential cause for the development of obesity. Given the high prevalence of obesity and its association with other cardiovascular and metabolic disorders, the subject of stress-induced eating has become even more important. We reviewed data from past studies to further elucidate the relationship between stress, appetite regulation and eating patterns in humans. Even though it is difficult to say with certainty that a person exposed to stress will undereat or overeat, but certain assumptions can be made. Generally, acute stress results in decreased eating whereas chronic stress results in increased eating. Glucocorticoids, the effector molecules of the stress response, increase the tendency to consume high-calorie, palatable foods. Further studies that can link the biological markers of stress-response with the hormones and neurotransmitters of appetite regulation can broaden our understanding of the subject. These studies can provide a groundwork for the development of effective anti-obesity strategies.