GenBank
GenBank
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DOI：
10.1093/nar/gkl986
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发表时间：
2010-01-01
影响因子：
14.9
通讯作者：
Sayers, Eric W.
中科院分区：
文献类型：
--
作者：
Benson, Dennis A.;Karsch-Mizrachi, Ilene;Sayers, Eric W.
GenBank (R) （http://www.ncbi.nlm.nih.gov）是一个综合性数据库，包含了近26万个正式描述物种的公开核苷酸序列。这些序列主要通过单个实验室的提交和大规模测序项目的批量提交获得，包括全基因组霰弹枪（WGS）和环境采样项目。大多数提交是使用基于网络的BankIt或独立的Sequin程序进行的，GenBank工作人员在收到数据后分配加入号。与欧洲核苷酸档案（ENA）和日本DNA数据库（DDBJ）的日常数据交换确保了全球范围的覆盖。GenBank可通过NCBI Entrez检索系统访问，该系统集成了来自主要DNA和蛋白质序列数据库的数据，以及分类、基因组、图谱、蛋白质结构和结构域信息，以及PubMed上的生物医学期刊文献。BLAST提供GenBank和其他序列数据库的序列相似性搜索。完整的GenBank数据库每两个月发布一次，每日更新一次，可通过FTP获得。要访问GenBank及其相关的检索和分析服务，请从NCBI主页开始：www.ncbi.nlm.nih.gov.GenBank((R)) （www.ncbi.nlm.nih.gov/genbank/）是一个全面的数据库，包含370,000个正式描述物种的公开核苷酸序列。这些序列主要通过单个实验室的提交和大规模测序项目的批量提交获得，包括全基因组霰弹枪（WGS）和环境采样项目。大多数提交是使用基于网络的BankIt或NCBI提交门户网站进行的。基因库工作人员在收到数据后分配入库编号。与欧洲核苷酸档案（ENA）和日本DNA数据库（DDBJ）的日常数据交换确保了全球范围的覆盖。基因库可以通过NCBI核苷酸数据库访问，该数据库链接到相关信息，如分类、基因组、蛋白质序列和结构，以及PubMed中的生物医学期刊文献。BLAST提供GenBank和其他序列数据库的序列相似性搜索。完整的GenBank数据库每两个月发布一次，每日更新一次，可通过FTP获得。最近的更新包括对序列标识符政策的更改，改进的16S提交向导，靶向位点研究，提交甲基化和BioNano映射文件的能力，以及抗微生物抗性基因数据库。GenBank (R)是一个综合性数据库，包含超过24万种已命名生物的公开核苷酸序列，主要通过单个实验室提交的文件和大规模测序项目的批量提交文件获得。大多数提交都是使用基于网络的BankIt或独立的Sequin程序进行的，并由GenBank工作人员在收到后分配加入编号。与欧洲EMBL数据库和日本DNA数据库的日常数据交换确保了全球范围的覆盖。GenBank可通过NCBI的检索系统Entrez访问，该系统集成了来自主要DNA和蛋白质序列数据库的数据，以及分类、基因组、图谱、蛋白质结构和结构域信息，以及PubMed上的生物医学期刊文献。BLAST提供GenBank和其他序列数据库的序列相似性搜索。完整的GenBank数据库每两个月发布一次，每日更新一次，可通过FTP获得。要访问GenBank及其相关的检索和分析服务，请从NCBI主页（www.ncbi.nlm.nih.gov）开始。GenBank(R)是一个全面的数据库，包含超过30万种属级或更低级别生物的公开核苷酸序列，主要通过个人实验室的提交和大规模测序项目的批量提交获得，包括全基因组鸟瞰图（WGS）和环境采样项目。大多数提交是使用基于网络的BankIt或独立的Sequin程序进行的，并且在收到后由GenBank工作人员分配加入编号。与欧洲分子生物学实验室核苷酸序列数据库和日本DNA数据库的日常数据交换确保了全球范围的覆盖。GenBank可通过NCBI Entrez检索系统访问，该系统集成了来自主要DNA和蛋白质序列数据库的数据，以及分类、基因组、图谱、蛋白质结构和结构域信息，以及PubMed上的生物医学期刊文献。BLAST提供GenBank和其他序列数据库的序列相似性搜索。GenBank数据库的完整双月发布和每日更新可通过FTP获得。要访问基因库及其相关的检索和分析服务，请从NCBI主页开始：www.ncbi.nlm.nih.gov。
GenBank (R) (http://www.ncbi.nlm.nih.gov) is a comprehensive database that contains publicly available nucleotide sequences for almost 260 000 formally described species. These sequences are obtained primarily through submissions from individual laboratories and batch submissions from large-scale sequencing projects, including whole-genome shotgun (WGS) and environmental sampling projects. Most submissions are made using the web-based BankIt or standalone Sequin programs, and GenBank staff assigns accession numbers upon data receipt. Daily data exchange with the European Nucleotide Archive (ENA) and the DNA Data Bank of Japan (DDBJ) ensures worldwide coverage. GenBank is accessible through the NCBI Entrez retrieval system, which integrates data from the major DNA and protein sequence databases along with taxonomy, genome, mapping, protein structure and domain information, and the biomedical journal literature via PubMed. BLAST provides sequence similarity searches of GenBank and other sequence databases. Complete bimonthly releases and daily updates of the GenBank database are available by FTP. To access GenBank and its related retrieval and analysis services, begin at the NCBI home page: www.ncbi.nlm.nih.gov.GenBank((R)) (www.ncbi.nlm.nih.gov/genbank/) is a comprehensive database that contains publicly available nucleotide sequences for 370 000 formally described species. These sequences are obtained primarily through submissions from individual laboratories and batch submissions from large-scale sequencing projects, including whole genome shotgun (WGS) and environmental sampling projects. Most submissions are made using the web-based BankIt or the NCBI Submission Portal. GenBank staff assign accession numbers upon data receipt. Daily data exchange with the European Nucleotide Archive (ENA) and the DNA Data Bank of Japan (DDBJ) ensures worldwide coverage. GenBank is accessible through the NCBI Nucleotide database, which links to related information such as taxonomy, genomes ,protein sequences and structures, and biomedical journal literature in PubMed. BLAST provides sequence similarity searches of GenBank and other sequence databases. Complete bimonthly releases and daily updates of the GenBank database are available by FTP. Recent updates include changes to policies regarding sequence identifiers, an improved 16S submission wizard, targeted loci studies, the ability to submit methylation and BioNano mapping files, and a database of anti-microbial resistance genes.GenBank (R) is a comprehensive database that contains publicly available nucleotide sequences for more than 240 000 named organisms, obtained primarily through submissions from individual laboratories and batch submissions from large-scale sequencing projects. Most submissions are made using the web-based BankIt or standalone Sequin programs and accession numbers are assigned by GenBank staff upon receipt. Daily data exchange with the EMBL Data Library in Europe and the DNA Data Bank of Japan ensures worldwide coverage. GenBank is accessible through NCBI's retrieval system, Entrez, which integrates data from the major DNA and protein sequence databases along with taxonomy, genome, mapping, protein structure and domain information, and the biomedical journal literature via PubMed. BLAST provides sequence similarity searches of GenBank and other sequence databases. Complete bimonthly releases and daily updates of the GenBank database are available by FTP. To access GenBank and its related retrieval and analysis services, begin at the NCBI Homepage (www.ncbi.nlm.nih.gov).GenBank(R) is a comprehensive database that contains publicly available nucleotide sequences for more than 300 000 organisms named at the genus level or lower, obtained primarily through submissions from individual laboratories and batch submissions from large-scale sequencing projects, including whole genome shotgun (WGS) and environmental sampling projects. Most submissions are made using the web-based BankIt or standalone Sequin programs, and accession numbers are assigned by GenBank staff upon receipt. Daily data exchange with the European Molecular Biology Laboratory Nucleotide Sequence Database in Europe and the DNA Data Bank of Japan ensures worldwide coverage. GenBank is accessible through the NCBI Entrez retrieval system, which integrates data from the major DNA and protein sequence databases along with taxonomy, genome, mapping, protein structure and domain information, and the biomedical journal literature via PubMed. BLAST provides sequence similarity searches of GenBank and other sequence databases. Complete bi-monthly releases and daily updates of the GenBank database are available by FTP. To access GenBank and its related retrieval and analysis services, begin at the NCBI homepage: www.ncbi.nlm.nih.gov.