Novel steroidal vinyl fluorides as inhibitors of steroid C17(20) lyase
Novel steroidal vinyl fluorides as inhibitors of steroid C17(20) lyase
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DOI：
10.1016/s0968-0896(01)00354-6
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发表时间：
2002-04-01
影响因子：
3.5
通讯作者：
Peet, NP
中科院分区：
文献类型：
--
作者：
Burkhart, JP;Weintraub, PM;Peet, NP
20-氟-17(20)-孕烯醇酮衍生物被设计为孕烯醇酮的烯醇模拟物。所有靶向的新型氟烯烃都是C-17(20)裂解酶的有效抑制剂。(C)2002爱思唯尔科学有限公司。保留所有权利。
20-Fluoro-17(20)-prognenolone derivatives were designed as enol mimics of pregnenolone. All of the targeted, novel fluoroolefins were potent inhibitors of C-17(20) lyase. (C) 2002 Elsevier Science Ltd. All rights reserved.