Single-Shot X-Ray Phase-Contrast Computed Tomography with Nonmicrofocal Laboratory Sources
Single-Shot X-Ray Phase-Contrast Computed Tomography with Nonmicrofocal Laboratory Sources
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DOI：
10.1103/physrevapplied.7.044029
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发表时间：
2017-04-28
影响因子：
4.6
通讯作者：
Olivo, A.
中科院分区：
文献类型：
--
作者：
Diemoz, P. C.;Hagen, C. K.;Olivo, A.
我们提出了一种方法，使执行X射线相衬成像（XPCI）计算机断层扫描与实验室设置使用单个图像每个投影角，消除了需要在采集过程中移动光学元件。给出了该方法的理论推导，并给出了其有效性条件。假设物体是准均质的，即，以表征折射率和线性衰减系数之间的比率，该比率在整个视场中近似恒定。该方法的实验证明，在塑料幻影和生物样品上使用连续旋转采集方案实现扫描时间为几分钟。此外，我们表明，这样的采集时间可以进一步减少与使用一个高效率的光子计数检测器。由于它能够大大简化图像采集过程并大大减少采集时间，我们相信这种方法代表了将XPCI应用于现实世界问题的非常重要的一步。
We present a method that enables performing x-ray phase-contrast imaging (XPCI) computed tomography with a laboratory setup using a single image per projection angle, eliminating the need to move optical elements during acquisition. Theoretical derivation of the method is presented, and its validity conditions are provided. The object is assumed to be quasihomogeneous, i.e., to feature a ratio between the refractive index and the linear attenuation coefficient that is approximately constant across the field of view. The method is experimentally demonstrated on a plastics phantom and on biological samples using a continuous rotation acquisition scheme achieving scan times of a few minutes. Moreover, we show that such acquisition times can be further reduced with the use of a high-efficiency photon-counting detector. Thanks to its ability to substantially simplify the image-acquisition procedure and greatly reduce collection times, we believe this method represents a very important step towards the application of XPCI to real-world problems.