Solitary fibrous tumour of the renal peripelvis
Solitary fibrous tumour of the renal peripelvis
复制标题
肾盂周围孤立性纤维瘤
DOI：
10.1046/j.1365-2559.1997.5570775.x
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发表时间：
1997
期刊：
影响因子：
6.4
通讯作者：
T. Nikaido
中科院分区：
文献类型：
--
作者：
M. Fukunaga;T. Nikaido
孤立性纤维肿瘤是一种罕见的梭形细胞肿瘤，通常与浆膜表面有关，尤其是胸膜。本报告描述了发生在肾盆周围的两个SFT，分别发生在33岁和36岁的女性。这些病变缺乏发生在肾脏的其他公认肿瘤的特征。免疫组织化学显示肿瘤细胞呈弥漫性强阳性，部分肿瘤细胞表达α-平滑肌肌动蛋白。流式细胞仪检测两种肿瘤均为二倍体。这两名患者都有良性的临床过程，分别获得了7.5年和1年的随访。这一发现表明，SFT可能起源于盆腔周围间充质细胞，这是SFT的一个新位置。肾盆和盆腔周围梭形细胞肿瘤的鉴别诊断应包括肾小管上皮细胞瘤。
Solitary fibrous tumours (SFTs) are rare spindle cell neoplasms generally associated with the serosal surface, especially the pleura. This report describes two SFTs arising in the renal peripelvis, occurring in 33‐ and 36‐year‐old females. The lesions lacked the characteristic features of other recognized neoplasms that occur in the kidney. Immunohistochemically, the tumour cells were diffusely and strongly positive for vimentin and CD34, and some tumour cells expressed alpha‐smooth muscle actin. Both tumours were diploid by flow cytometry. Both patients have had benign clinical courses with 7.5‐ and 1‐year follow‐up. The findings suggest that the SFTs may originate from peripelvic mesenchymal cells, a new location for SFT. SFT should be included in the differential diagnosis of spindle cell tumours arising in the renal pelvis and peripelvis.