Medial temporal lobe contributions to short-term memory for faces.
Medial temporal lobe contributions to short-term memory for faces.
复制标题
内侧颞叶对面部短期记忆的贡献。
DOI：
10.1037/a0033612
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发表时间：
2013
期刊：
影响因子：
--
通讯作者：
Verfaellie,Mieke
中科院分区：
文献类型：
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作者：
Race,Elizabeth;LaRocque,KarenF;Keane,MargaretM;Verfaellie,Mieke
内侧颞叶（MTL）在短时记忆（STM）中的作用仍然是一个有争议的问题。虽然成像研究通常显示海马激活在短延迟记忆任务，证据与MTL病变的健忘症患者是混合的。有人认为，遗忘症中明显的STM损伤可能反映了长期记忆（LTM）对表现的贡献。我们挑战这一结论，证明MTL健忘症患者表现出受损的延迟匹配到样本（DMS）的脸在一个任务，满足传统的延迟为基础的和最近提出的干扰为基础的标准分类为STM任务。在实验1中，我们证明了我们的脸DMS任务符合所提出的基于分心物的STM分类标准，在延迟期分心物刺激的广泛处理破坏了健康个体的表现。在实验2中，MTL健忘症患者的病变延伸到前海马下皮层，但不限于海马病变的患者，在这项任务上表现受损，没有分心延迟短至8秒，在时间范围内的延迟为基础的STM分类，在完整的感知匹配性能的背景下。实验3通过表明健康受试者的表现被干扰的程度取决于分心物任务的视觉要求，为面孔短时记忆依赖于视觉加工的假设提供了支持。总之，这些研究结果是一致的概念，即记忆障碍的STM的面孔反映了赤字与海马下皮层相关的神经加工，并提供了新的证据，MTL支持超越LTM域的认知。（PsycINFO数据库记录（c）2019阿帕，保留所有权利）
The role of the medial temporal lobes (MTL) in short-term memory (STM) remains a matter of debate. Whereas imaging studies commonly show hippocampal activation during short-delay memory tasks, evidence from amnesic patients with MTL lesions is mixed. It has been argued that apparent STM impairments in amnesia may reflect long-term memory (LTM) contributions to performance. We challenge this conclusion by demonstrating that MTL amnesic patients show impaired delayed matching-to-sample (DMS) for faces in a task that meets both a traditional delay-based and a recently proposed distractor-based criterion for classification as an STM task. In Experiment 1, we demonstrate that our face DMS task meets the proposed distractor-based criterion for STM classification, in that extensive processing of delay-period distractor stimuli disrupts performance of healthy individuals. In Experiment 2, MTL amnesic patients with lesions extending into anterior subhippocampal cortex, but not patients with lesions limited to the hippocampus, show impaired performance on this task without distraction at delays as short as 8 s, within temporal range of delay-based STM classification, in the context of intact perceptual matching performance. Experiment 3 provides support for the hypothesis that STM for faces relies on configural processing by showing that the extent to which healthy participants’ performance is disrupted by interference depends on the configural demands of the distractor task. Together, these findings are consistent with the notion that the amnesic impairment in STM for faces reflects a deficit in configural processing associated with subhippocampal cortices and provide novel evidence that the MTL supports cognition beyond the LTM domain.(PsycINFO Database Record (c) 2019 APA, all rights reserved)