Initial results from the Sherbrooke avalanche photodiode positron tomograph
Initial results from the Sherbrooke avalanche photodiode positron tomograph
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DOI：
10.1109/23.507252
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发表时间：
1996-06-01
影响因子：
1.8
通讯作者：
Msaki, P
中科院分区：
文献类型：
--
作者：
Lecomte, R;Cadorette, J;Msaki, P
基于雪崩光电二极管 (APD) 探测器的 PET 系统的设计特点和工程限制已在之前的报告中进行了描述。在本文中，我们介绍了使用 Sherbrooke APD-PET 扫描仪获得的初步结果，这是一种非常高空间分辨率的设备，专为大鼠、猫、兔子和小猴子等中小型实验动物的动态成像而设计。其物理性能已根据分辨率、灵敏度、计数率、随机和散射分数、对比度和相对活动恢复（作为物体大小的函数）进行了评估。扫描仪用于生物医学研究应用的功能已通过模型和动物研究得到证明。
The design features and engineering constraints of a PET system based on avalanche photodiode (APD) detectors have been described in a previous report. In this paper, we present the initial results obtained with the Sherbrooke APD-PET scanner, a very high spatial resolution device designed for dynamic imaging of small and medium-sized laboratory animals such as rats, cats, rabbits and small monkeys. Its physical performance has been evaluated in terms of resolution, sensitivity, count rate, random and scatter fractions, contrast and relative activity recovery as a function of object size. The capabilities of the scanner for biomedical research applications have been demonstrated using phantom and animal studies.