Small intrapulmonary artery lung prototypes. Mathematical modeling of gas transfer.
Small intrapulmonary artery lung prototypes. Mathematical modeling of gas transfer.
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小肺内动脉肺原型。
DOI：
10.1097/00002480-199609000-00058
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发表时间：
1996
期刊：
影响因子：
--
通讯作者：
Snider,MT
中科院分区：
文献类型：
--
作者：
Baskaran,H;Nodelman,V;Ultman,JS;Richard,RB;Panol,G;High,KM;Snider,MT
两个扩散模型已被开发，以分析气体传输数据先前测量的血管内人工肺由一个中央供气导管，从其中拴着大量的盲端微孔纤维的长度相等。对流扩散模型（CD）描述了当在恒定压力条件下供应气体时二元气体对的逆流转移，并且良好混合（WM）循环压力模型预测了当气体供应压力在压缩和真空条件之间时间循环时的转移。用CD模型对气-气和液-气排泄数据进行回归，得到液相传质系数k AI的估计值。由于这些值介于平行于圆柱体的流动和垂直于圆柱体的流动的预期k AI之间，因此气体传输受到几乎垂直于试验段轴线的纤维系留区域和沿着试验段壁放置的纤维自由端的影响。与
Two diffusion models have been developed to analyze gas transfer data previously measured in an intravascular artificial lung consisting of a central gas supply catheter from which are tethered a large number of blind-ended microporous fibers of equal length. A convective-diffusion model (CD) describes the countercurrent transfer of a binary gas pair when gas is supplied at constant pressure conditions, and a well mixed (WM) cycled pressure model predicts transfer when the gas supply pressure is time cycled between compression and vacuum conditions. Regression of gas to gas and liquid to gas excretion data with the CD model resulted in estimates of the liquid phase mass transfer coefficient k AI. Because these values were intermediate between the k AI expected for flow parallel to a cylinder and for flow normal to a cylinder, gas transfer was influenced by both the tethered region of the fiber that was nearly perpendicular to the axis of the test section and the free end of the fiber that rested along the wall of the test section. With