Controversial issues and possible answers on the antigen-specific regulation of the IgE antibody response.
Controversial issues and possible answers on the antigen-specific regulation of the IgE antibody response.
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关于 IgE 抗体反应的抗原特异性调节的争议问题和可能的答案。
DOI：
10.1007/978-1-4615-5855-2_45
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发表时间：
1996
影响因子：
--
通讯作者：
Mori,A
中科院分区：
文献类型：
--
作者：
Ishizaka,K;Nakano,T;Ishii,Y;Liu,YC;Mikayama,T;Mori,A
在过去的10年中，许多研究者调节IgE抗体反应的主要方法集中在IgE合成的同种型特异性抑制。然而，要考虑的另一种方法是抑制对过敏患者敏感的过敏原的抗体应答。在本报告中，我们将讨论以抗原特异性方式调节抗体反应的可能性，以及这种机制存在的科学证据。
In the past 10 years, the major approaches for the regulation of the IgE antibody response by many investigators have been focused to isotype-specific suppression of the IgE synthesis. However, another approach to be considered is to suppress the antibody response to the allergens to which the allergic patients are sensitive. In this presentation, we would like to discuss the possibility to regulate the antibody response in antigen-specific manner, and scientific evidence for the presence of such a mechanism.