MYOSIN ROD PHOSPHORYLATION AND THE CATCH STATE OF MOLLUSCAN MUSCLES
MYOSIN ROD PHOSPHORYLATION AND THE CATCH STATE OF MOLLUSCAN MUSCLES
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DOI：
10.1126/science.3026049
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发表时间：
1987-01-16
期刊：
影响因子：
56.9
通讯作者：
COHEN, C
中科院分区：
文献类型：
--
作者：
CASTELLANI, L;COHEN, C
机械测量显示，软体动物平滑肌肉[Mytilus edulis]的张力状态持续时间较长，与蛋白质磷酸化水平有关。从这些肌肉中分离出的肌球蛋白是不寻常的，因为在杆状部分被内源性激酶磷酸化，就像某些非肌肉肌球蛋白一样。这些发现表明，肌球蛋白棒是磷酸化的目标，这一反应可能控制着从捕获到松弛的转变。
"Catch" is a prolonged state of tension in molluscan smooth muscles [Mytilus edulis] shown by mechanical measurements to be associated with the level of protein phosphorylation. Myosin isolated from these muscles is unusual in being phosphorylated in the rod portion by an endogenous kinase, like certain nonmuscle myosins. These findings suggest that the myosin rod is a target for phosphorylation and that this reaction may control the transition from catch to relaxation.