The epidemiology of Wegener's granulomatosis - Estimates of the five-year period prevalence, annual mortality, and geographic disease distribution from population-based data sources
The epidemiology of Wegener's granulomatosis - Estimates of the five-year period prevalence, annual mortality, and geographic disease distribution from population-based data sources
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DOI：
10.1002/art.1780390112
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发表时间：
1996-01-01
影响因子：
--
通讯作者：
Kaslow, RA
中科院分区：
文献类型：
--
作者：
Cotch, MF;Hoffman, GS;Kaslow, RA
目标。估计韦格纳肉芽肿病的患病率、年死亡率和地理分布。分析来自全国调查和所有纽约州住院机构的国家生命统计数据和住院数据。结果。1979年至1988年间，美国有1784份死亡证明将韦格纳肉芽肿病列为死亡原因，在全国范围内，估计有10771例住院治疗将韦格纳肉芽肿病列入出院诊断，在纽约州，571例韦格纳肉芽肿患者中有978例住院治疗。在美国，韦格纳肉芽肿病的患病率约为每10万人中有3.0人，当分析单个县的发病率时，韦格纳肉芽肿病的地理分布明显不同。与先前的报告相反，疾病恶化与季节之间的关联并不明显。
Objective. To estimate the prevalence, annual mortality, and geographic distribution of Wegener's granulomatosis.Methods. Analysis of national vital statistics data and hospitalization data from a national survey and from ail New York State inpatient facilities.Results. Between 1979 and 1988, 1,784 death certificates in the United States listed Wegener's granulomatosis as a cause of death, Nationally, an estimated 10,771 hospitalizations included Wegener's granulomatosis among the discharge diagnoses, In New York State, there were 978 hospitalizations among 571 individuals with Wegener's granulomatosis.Conclusion. The prevalence of Wegener's granulomatosis in the United States is approximately 3.0 per 100,000 persons, Clear differences in the geographic distribution of Wegener's granulomatosis are apparent when analyses consider rates of disease in individual counties. Contrary to previous reports, associations between disease exacerbations and season were not apparent.