ANGIOTENSIN AND ANGIOTENSIN CONVERTING ENZYME TISSUE-LEVELS IN 2-KIDNEY, ONE CLIP HYPERTENSIVE RATS
ANGIOTENSIN AND ANGIOTENSIN CONVERTING ENZYME TISSUE-LEVELS IN 2-KIDNEY, ONE CLIP HYPERTENSIVE RATS
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DOI：
10.1161/01.hyp.20.6.763
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发表时间：
1992-12-01
期刊：
影响因子：
8.3
通讯作者：
NAVAR, LG
中科院分区：
文献类型：
--
作者：
GUAN, S;FOX, J;NAVAR, LG
在两肾一夹高血压大鼠的初始（7天）和维持（25天）阶段，在两个肾脏中测定肾组织血管紧张素I（Ang I）和II（Ang II）含量和血管紧张素转换酶活性。在第7天和第25天，动脉收缩压分别为146+/-2和170+/-7 mm Hg。7天后，肾组织中Ang I含量分别增加64%和70%（p < 0.01），
Renal tissue angiotensin I (Ang I) and II (Ang II) content and angiotensin converting enzyme activity were assessed in both kidneys during initial (7 days) and maintenance (25 days) phases of two-kidney, one clip hypertension in rats. At 7 and 25 days, systolic arterial pressure was 146+/-2 and 170+/-7 mm Hg, respectively. After 7 days, Ang I content of clipped kidneys was 64% and 70% higher (p