CORRELATION OF BLOOD-PRESSURE WITH PLASMA ASCORBIC-ACID
CORRELATION OF BLOOD-PRESSURE WITH PLASMA ASCORBIC-ACID
复制标题
DOI：
10.1016/s0271-5317(05)80470-1
复制
发表时间：
1991-12-01
影响因子：
4.5
通讯作者：
JACOB, RA
中科院分区：
文献类型：
--
作者：
CHOI, ESK;JACQUES, PF;JACOB, RA
在一项针对247名年龄在60-96岁的华裔美国人（男性38%，女性62%）的营养调查中，发现他们的平均血浆抗坏血酸低于美国白人。通过协方差分析和多元回归分析，调整年龄、性别、体重指数、烟酒消费、膳食钠钾比、血清钙磷比和体力活动水平等因素，探讨血压与血浆抗坏血酸的关系。血浆抗坏血酸与收缩压（p < 0.001）和舒张压（p < 0.001）呈负相关。血浆抗坏血酸最低四分位数的受试者的平均收缩压比最高四分位数的受试者高17.6 mm Hg；他们的平均舒张压高出5.5 mm Hg。我们推测亚临床维生素C缺乏可能是华裔美国人高血压的危险因素。
In a nutrition survey of 247 Chinese Americans (38% men and 62% women) aged 60-96, the mean plasma ascorbic acid was found to be lower than that of white Americans. The association between their blood pressure and plasma ascorbic acid was explored by analysis of covariance and multiple regression, adjusting for age, sex, body mass index, alcohol and cigarette consumption, dietary Na:K ratio, serum Ca:P ratio and physical activity level. Inverse associations were observed between plasma ascorbic acid and systolic blood pressure (p < .001) and diastolic blood pressure (p < .001). Subjects in the lowest quartile of plasma ascorbic acid had a mean systolic blood pressure which was 17.6 mm Hg higher than those in the highest quartile; their mean diastolic blood pressure was higher by 5.5 mm Hg. We speculate that subclinical vitamin C deficiency may be a risk factor for hypertension in Chinese Americans.