Nutritional Management Enhances the Recovery of Swallowing Ability in Older Patients with Sarcopenic Dysphagia.
Nutritional Management Enhances the Recovery of Swallowing Ability in Older Patients with Sarcopenic Dysphagia.
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DOI：
10.3390/nu13020596
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发表时间：
2021-02-11
期刊：
影响因子：
5.9
通讯作者：
The Japanese Working Group On Sarcopenic Dysphagia
中科院分区：
文献类型：
--
作者：
Shimizu A;Fujishima I;Maeda K;Wakabayashi H;Nishioka S;Ohno T;Nomoto A;Kayashita J;Mori N;The Japanese Working Group On Sarcopenic Dysphagia
本研究评估了肌少性吞咽困难患者≥30 kcal/理想体重（IBW）/天（kg）的高能量提供是否能有效改善吞咽能力和日常生活活动（ADL）。在急性后住院的 110 名肌肉减少性吞咽困难患者（平均年龄，84.9 ± 7.4 岁）中，分别使用食物摄入水平量表 (FILS) 和功能独立测量 (FIM) 评估吞咽能力和 ADL。主要结局是出院时的 FILS，次要结局是出院时达到最小临床重要差异 (MCID) 的 FIM。我们使用治疗加权逆概率 (IPTW) 方法创建了一个均质概率模型，在住院 1 周期间平均提供能量≥30 kcal/IBW/天 (kg) 的情况下，没有统计学上的显着差异，并比较了组间的结果。 62.7% 的患者平均提供的能量≥30 kcal/IBW/天（kg）。在 IPTW 模型中，平均提供能量≥30 kcal/IBW/天（kg）组的 FILS 和出院时 FIM 达到 MCID 的比率显着较高（分别为 p = 0.004 和 p < 0.001）。为肌肉减少性吞咽困难患者提供高能量可以改善吞咽能力并产生具有临床意义的功能结果。
This study assessed whether a high provided energy of ≥30 kcal/ideal body weight (IBW)/day (kg) for patients with sarcopenic dysphagia effectively improved swallowing ability and the activities of daily living (ADLs). Among 110 patients with sarcopenic dysphagia (mean age, 84.9 ± 7.4 years) who were admitted to a post-acute hospital, swallowing ability and the ADLs were assessed using the Food Intake LEVEL Scale (FILS) and the Functional Independence Measure (FIM), respectively. The primary outcome was the FILS at discharge, while the secondary outcome was the achievement of the FIM with a minimal clinically important difference (MCID) at discharge. We created a homogeneous probability model without statistically significant differences using the inverse probability of treatment weighting (IPTW) method with and without a mean provided energy of ≥30 kcal/IBW/day (kg) for a period of 1 week of hospitalization and compared the outcomes between groups. A mean provided energy of ≥30 kcal/IBW/day (kg) was achieved in 62.7% of patients. In the IPTW model, the FILS and the rates of achieved MCID of the FIM at discharge were significantly higher in the mean provided energy of ≥30 kcal/IBW/day (kg) group (p = 0.004 and p < 0.001, respectively). A high provided energy for patients with sarcopenic dysphagia may improve swallowing ability and produce clinically meaningful functional outcomes.
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影响因子：
5.9
作者：
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