Effects of Resistance or Aerobic Exercise Training on Interleukin-6, C-Reactive Protein, and Body Composition
Effects of Resistance or Aerobic Exercise Training on Interleukin-6, C-Reactive Protein, and Body Composition
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DOI：
10.1249/mss.0b013e3181b117ca
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发表时间：
2010-02-01
期刊：
影响因子：
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通讯作者：
Drinkwater, Eric J.
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文献类型：
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作者：
Donges, Cheyne E.;Duffield, Rob;Drinkwater, Eric J.
东格斯角E、R.达菲尔德和E. J.饮用水。阻力或有氧运动训练对白细胞介素-6、C反应蛋白和身体成分的影响。医学科学体育锻炼：第42卷，第2期，第100页。304-313，2010年。目的：观察10周抗阻或有氧运动训练对白细胞介素-6（IL-6）和C反应蛋白（CRP）的影响。此外，确定训练前和训练后IL-6和CRP的变化与全身脂肪量（TB-FM）、腹内脂肪量（IA-FM）和全身瘦体重（TB-LM）的变化之间的相关性。方法：将102名久坐受试者分为阻力组（n = 35）、有氧组（n = 41）和对照组（n = 26）。在干预前后，受试者参与双能X射线吸收测定法、肌肉力量和有氧健身测量，并进一步提供静息空腹静脉血样本用于测量IL-6、CRP、胆固醇谱、甘油三酯、葡萄糖、胰岛素和糖化血红蛋白。阻力组和有氧组分别完成为期10周的监督和周期性的训练计划，而对照组保持久坐的生活方式和饮食模式。结果如下：两种运动训练方案均未降低IL-6水平，但阻力组和有氧组分别使CRP降低32.8%（P < 0.05）和16.1%（P = 0.06）。基线时，CRP与IL-6（r = 0.35）、（TB-FM）（r = 0.36）和IA-FM（r = 0.31）呈正相关，与有氧适应性指标呈负相关（所有r值>= -0.24）。与阻力组和对照组相比，有氧运动组的各项有氧体能指标均显著提高（P < 0.05），IA-FM（7.4%）和体质量（1.1%）显著降低。与有氧运动组和对照组相比，阻力组TB-FM分别提高3.7%、46.3%和56.6%（P < 0.05）。身体强度结论：尽管与有氧训练组相比，基线IL-6没有改变，脂肪组织测量值的减少显著较小，但只有阻力运动训练导致CRP浓度显著降低。
DONGES, C. E., R. DUFFIELD, and E. J. DRINKWATER. Effects of Resistance or Aerobic Exercise Training on Interleukin-6, C-Reactive Protein, and Body Composition. Med. Sci. Sports Exerc., Vol. 42, No. 2, pp. 304-313, 2010. Purpose: To determine the effects of 10 wk of resistance or aerobic exercise training on interleukin-6 (IL-6) and C-reactive protein (CRP). Further, to determine pretraining and posttraining associations between alterations of IL-6 and CRP and alterations of total body fat mass (TB-FM), intra-abdominal fat mass (IA-FM), and total body lean mass (TB-LM). Methods: A sample of 102 sedentary subjects were assigned to a resistance group (n = 35), an aerobic group (n = 41), or a control group (n = 26). Before and after intervention, subjects were involved in dual-energy x-ray absorptiometry, muscular strength and aerobic fitness, measurements and further provided a resting fasted venous blood sample for measures of IL-6, CRP, cholesterol profile, triglycerides, glucose, insulin, and glycosylated hemoglobin. The resistance and the aerobic groups completed a respective 10-wk supervised and periodized training program, whereas the control group maintained sedentary lifestyle and dietary patterns. Results: Both exercise training programs did not reduce IL-6; however, the resistance and the aerobic groups reduced CRP by 32.8% (P < 0.05) and 16.1% (P = 0.06), respectively. At baseline, CRP was positively correlated with IL-6 (r = 0.35), (TB-FM) (r = 0.36), and IA-FM (r = 0.31) and was inversely con-elated with aerobic fitness measures (ail r values >= -0.24). Compared with the resistance and the control groups, the aerobic group exhibited significant (P < 0.05) improvements in all aerobic fitness measures and significant reductions in IA-FM (7.4%) and body mass (1.1%). Compared with the aerobic and the control groups, the resistance group significantly (P < 0.05) improved TB-FM (3.7%) and upper (46.3%) and lower (56.6%.) body strength. Conclusion: Despite no alteration in baseline IL-6 and significantly smaller reductions in measures of adipose tissue as compared with the aerobic training group, only resistance exercise training resulted in significant attenuation of CRP concentration.