RECIPROCAL INHIBITION IN WRITERS CRAMP
RECIPROCAL INHIBITION IN WRITERS CRAMP
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DOI：
10.1002/mds.870100505
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发表时间：
1995-09-01
影响因子：
8.6
通讯作者：
LU, CS
中科院分区：
文献类型：
--
作者：
CHEN, RS;TSAI, CH;LU, CS
本文观察了13例书写痉挛患者（单纯型8例，张力障碍型5例）和14例正常人（酸）的桡神经条件刺激对正中H反射的抑制作用。患者和对照组均为右撇子，研究对象为他们的右臂。在13名患者中的9名中也研究了无症状的左臂。在对照组中，我们确定了三个抑制期，最大峰值出现在条件试验间隔0 ms（41 +/- 17%）、20 ms（40 +/- 13%）和100 ms（36 +/- 20%）。在患者组中，这三个时期的抑制幅度在两个手臂中均显著小于对照组。然而，有症状和无症状组之间这三个时期的抑制幅度无显著差异。单纯性和张力障碍性书写痉挛之间也没有显著差异。我们的研究结果表明，相互抑制的衰减不仅存在于有症状的武器，但也在无症状的作家痉挛患者的武器。在无症状的手的相互抑制的缺陷从来没有被记录。我们认为，先前存在的电生理异常可能为转移书写后手抽筋的发生提供了解释。
We studied the inhibition of median H-reflexes by conditioning stimuli on the radial nerve in 13 patients with writer's cramp, eight of the simple type and five of the dystonic type, acid in 14 normal volunteers. The patients and controls were right-handed, and their right arms were studied. Asymptomatic left arms were also studied in nine of 13 patients. In the control group we identified three periods of inhibition, with maximum peaks at conditioning-test intervals of 0 ms (41 +/- 17%), 20 ms (40 +/- 13%), and 100 ms (36 +/- 20%). In the patient group, the amplitudes of inhibition of these three periods in both arms were significantly less than those in the control group. However, there were no significant differences in the amplitudes of inhibition of these three periods between symptomatic and asymptomatic arms. There were also no significant differences between simple and dystonic writer's cramps. Our results indicate that the attenuation of reciprocal inhibition was present not only in symptomatic arms but also in asymptomatic arms of patients with writer's cramp. The defect of reciprocal inhibition in the asymptomatic hand has never been documented. We suggest that the preexistent electrophysiological abnormality may provide an explanation for the development of hand cramp after shifted writing.