Black Creek Canal Virus infection in Sigmodon hispidus in southern Florida
Black Creek Canal Virus infection in Sigmodon hispidus in southern Florida
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DOI：
10.4269/ajtmh.1998.59.699
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发表时间：
1998-11-01
影响因子：
3.3
通讯作者：
Childs, JE
中科院分区：
文献类型：
--
作者：
Glass, GE;Livingstone, W;Childs, JE
在佛罗里达南部1,600公里的研究区域内的89个地点，共收集了1,500只小型哺乳动物，并对它们进行了与辛诺布尔病毒（汉坦病毒：布尼亚病毒科）交叉反应的抗体检测。超过95%的123只血清反应阳性动物是棉鼠（Sigmodon hispidus），表明感染了黑溪运河病毒，尽管也捕获了血清反应性大鼠（5/294）和棉鼠（1/39）。S.硬毛占11%。血清阳性率随体型增大而增加，男性（18%; n = 451）比女性（6%; n = 593）更常见。内感染S. hispidus种群在整个研究区域广泛分布。患病率范围从0%到60%，在网站上超过5棉鼠采样，但不仅是一个函数的样本量。与没有血清阳性棉鼠的站点相比，血清阳性棉鼠的站点在地理上聚集。集群是不是由于空间分布的网站，很少的动物，收集季节，或在这些父系捕获的动物的性别偏见。然而，在无血清阳性动物的研究中心，中等体型动物（60-99 g）过多，最大和最小动物不足。这些数据表明，人口结构内的栖息地镶嵌可能发挥重要作用，汉坦病毒感染的空间分布在当地人口的水库物种。
A total of 1,500 small mammals were collected and tested for antibodies cross-reactive to Sin Nombre virus (Hantavirus: Bunyaviridae) at 89 sites in a 1,600 km: study area of southern Florida. More than 95% of the 123 seropositive animals were cotton rats (Sigmodon hispidus), suggesting infection by Black Creek Canal Virus, although seroreactive Rattus rattus (5 of 294) and Peromyscus gossypinus (1 of 39) also were captured. Crude seroprevalence in S. hispidus was 11%. Seroprevalence increased with body size and was more common in male (18%; n = 451) than in female (6%; n = 593) cotton Fats. Infection within S. hispidus populations was widespread throughout the study area. Prevalence ranged from 0% to 60% at sites where more than five cotton rats were sampled but was not only a function of sample size. Sites with seropositive cotton rats were geographically clustered compared with sites with no seropositive cotton rats. Clustering was not due to the spatial distribution of sites with few animals, season of collection, or sex bias of animals captured at these sires. However, sites with no seropositive animals had an excess of animals in the intermediate size class (60-99 g) and a deficit of the largest and smallest animals. These data suggest that population structure within the habitat mosaic may play a significant role in the spatial distribution of hantavirus infection in local populations of reservoir species.