Relationship between negative affect and smoking topography in heavy drinking smokers
Relationship between negative affect and smoking topography in heavy drinking smokers
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DOI：
10.1016/j.addbeh.2016.05.016
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发表时间：
2016-10-01
影响因子：
4.4
通讯作者：
Ray, Lara A.
中科院分区：
文献类型：
--
作者：
Green, ReJoyce;Bujarski, Spencer;Ray, Lara A.
大量饮酒的吸烟者代表了一个相当大的吸烟者亚组，对他们来说，尼古丁剥夺和酒精使用增加了实验室中吸烟的冲动，并预测了戒烟过程中的失误。个人吸烟的方式（即吸烟地形图）提供了一个可靠的吸烟强度和强化指数，但影响吸烟地形图的影响还没有彻底检查大量饮酒的吸烟者。当前的研究探讨了影响和尼古丁剥夺如何预测吸烟行为，参与者（N = 27）在尼古丁戒断12小时后和酒精引发剂量（目标BrAC = 0.06 g/dl）后使用吸烟地形图装置吸烟。主要吸烟地形测量指标是抽吸量、速度、持续时间和抽吸间隔（IPI）。采用明尼苏达尼古丁戒断量表（MNWS）和情绪状态量表（POMS）测定尼古丁剥夺的效果。在基线（即尼古丁戒断和饮酒前12小时）和饮酒后30分钟（即BrAC峰值）获得测量值。结果显示，在吸烟过程中，启动后的负面影响显著调节了吸烟量、吸烟持续时间和IPI的轨迹（p < 0.05），使得那些具有更大负面影响的人在吸烟量和吸烟持续时间方面具有更平坦的斜率，并且吸烟次数越来越少。我们的研究结果表明，尼古丁剥夺后的基线和启动后负面影响改变了吸烟模式，并增加了单支香烟中的尼古丁暴露。未来的研究需要检查重度饮酒吸烟者对酒精和吸烟反应的尼古丁剥夺差异。(C)2016爱思唯尔有限公司版权所有
Heavy drinking smokers represent a sizeable subgroup of smokers for whom nicotine deprivation and alcohol use increases the urge to smoke in the laboratory and predicts lapses during smoking cessation. The manner in which individuals smoke a cigarette (i.e. smoking topography) provides a reliable index of smoking intensity and reinforcement, yet the effects of affect on smoking topography have not been thoroughly examined in heavy drinking smokers. The current study examined how affect and nicotine deprivation predict smoking behavior as participants (N = 27) smoked one cigarette using a smoking topography device after 12-h of nicotine abstinence and after a priming dose of alcohol (target BrAC = 0.06 g/dl). Primary smoking topography measures were puff volume, velocity, duration, and inter-puff interval (IPI). The effect of nicotine deprivation was measured by the Minnesota Nicotine Withdrawal Scale (MNWS) and the Profile of Mood States (POMS). Measures were obtained at baseline (i.e. 12-h of nicotine abstinence and pre-alcohol) and 30-minutes after alcohol administration (i.e. peak BrAC). Results revealed post-priming negative affect significantly moderated the trajectories of puff volume, puff duration and IPI (p's < 0.05) over the course of the cigarette, such that those with greater negative affect had flatter slopes for volume and duration and increasingly infrequent puffs. Our results suggest that baseline and post-priming negative affect following nicotine deprivation alters smoking patterns and increases nicotine exposure throughout a single cigarette. Future studies need to examine differential amounts of nicotine deprivation on response to alcohol and smoking in heavy drinking smokers. (C) 2016 Elsevier Ltd. All rights reserved.