δ‐aminolevulinate dehydrase: a new genetic polymorphism in man
δ‐aminolevulinate dehydrase: a new genetic polymorphism in man
复制标题
δ-氨基乙酰丙酸脱水酶：人类新的遗传多态性
作者：
G. Battistuzzi;R. Petrucci;L. Silvagni;F. Urbani;S. Caiola
建立了人红细胞δ-氨基乙酰丙酸脱氢酶（ALADH）的电泳和定量分析方法。该酶受常染色体基因控制，在意大利人群中有两个常见的共显性等位基因ALADH 1和ALADH 2，频率分别为0-89和Oil。平均表型酶活性几乎相同：ALADH 1、2 - 1和2表型分别为52、49和55 mIU/g Hb。
A method has been developed for the electrophoretic and quantitative analyses of human red cell δ‐aminolevulinate dehydrase (ALADH). The enzyme is under the control of an autosomal gene, with two common codominant alleles, ALADH1 and ALADH2, with frequencies of 0–89 and Oil, respectively, in the Italian population. Mean phenotypic enzyme activities are nearly identical: 52, 49 and 55 mlU/g Hb for ALADH 1, 2‐1 and 2 phenotypes respectively.