Respirator Testing Using Virus Aerosol: Comparison between Viability Penetration and Physical Penetration.
Respirator Testing Using Virus Aerosol: Comparison between Viability Penetration and Physical Penetration.
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使用病毒气溶胶进行呼吸器测试：活力渗透和物理渗透之间的比较。
DOI：
10.1093/annhyg/mev019
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发表时间：
2015
期刊：
影响因子：
--
通讯作者：
Pui,DavidYH
中科院分区：
文献类型：
--
作者：
Zuo,Zhili;Kuehn,ThomasH;Pui,DavidYH
比较了MS2噬菌体通过三种不同型号过滤器中使用的过滤介质的活力、荧光（颗粒体积）、光度、病毒RNA和颗粒数渗透，以更好地了解活力和物理渗透之间的相关性。虽然粒子体积穿透比粒子数穿透更好地代表了活力和病毒RNA穿透，但它们比光度穿透低几倍，这部分是由于上游和下游气溶胶样品之间的病毒存活差异。结果表明，目前基于NIOSH光度计的测试方法可以用作一种快速手段，以大致区分对病毒气溶胶具有不同性能的净化器。
Viability, fluorescence (particle volume), photometric, viral RNA, and particle number penetration of MS2 bacteriophage through filter media used in three different models of respirators were compared to better understand the correlation between viability and physical penetration. Although viability and viral RNA penetration were better represented by particle volume penetration than particle number penetration, they were several-fold lower than photometric penetration, which was partially due to the difference in virus survival between upstream and downstream aerosol samples. Results suggest that the current NIOSH photometer-based test method can be used as a quick means to roughly differentiate respirators with different performance against virus aerosols.