Analysis of the infection system of human T‐cell leukaemia virus type I based on a mathematical epidemic model

Analysis of the infection system of human T‐cell leukaemia virus type I based on a mathematical epidemic model
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基于数学流行病模型的人类T细胞白血病病毒I型感染系统分析

DOI:
10.1002/sim.1010
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发表时间:
2001
影响因子:
2
通讯作者:
T. Taguchi
T. Taguchi
中科院分区:
医学3区
文献类型:
--
作者:
N. Eshima;M. Tabata;H. Kikuchi;S. Karukaya;T. Taguchi

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人类 T 细胞白血病病毒 I 型 (HTLV-I) 是一种导致成人 T 细胞白血病 (ATL) 的逆转录病毒。 HTLV-I 在日本人体内已经存在了数千年。为了预防 HTLV-I 的流行,用数学方法解释感染系统非常重要。从日本的主要感染途径来看,即:(i)母婴传播; (ii) 男性(丈夫)向女性(妻子)传播; (iii)女性(妻子)到男性(丈夫)的传播,可以构建描述感染比例随时间变化的数学模型。该模型给出了目前每年男性向女性传播和女性向男性传播的感染率上限,并从数学模型中推导出与HTLV-I感染相关的理论结果。基于本模型的模拟研究证明了与 HTLV-I 感染相关的理论结果。版权所有 © 2001 约翰·威利父子有限公司
Human T‐cell leukaemia virus type I (HTLV‐I) is a retrovirus that causes adult T‐cell leukaemia (ATL). HTLV‐I has existed in Japanese people for thousands of years. In order to prevent an epidemic of HTLV‐I, it is important to explain the infection system by a mathematical approach. By considering the main infection routes in Japan, that is: (i) mother‐to‐child transmission; (ii) male (husband)‐to‐female (wife) transmission; and (iii) female (wife)‐to‐male (husband) transmission, a mathematical model for describing the time‐dependent change of the infection proportion can be constructed. An upper bound of the present infection rate per year in male‐to‐female transmission and that in female‐to‐male transmission is given by the model, and theoretical results related to HTLV‐I infection are also deduced from the mathematical model. A simulation study based on the present model demonstrates the theoretical results relating to the HTLV‐I infection. Copyright © 2001 John Wiley & Sons, Ltd.
牙买加人类 T 细胞嗜淋巴细胞病毒 I 型 (HTLV-I) 的母婴传播:与包膜糖蛋白 (gp46) 表位抗体的关联。
DOI: --
发表时间: 1993
期刊: Journal of acquired immune deficiency syndromes
影响因子: --
作者:
Wiktor,SZ;Pate,EJ;Murphy,EL;Palker,TJ;Champegnie,E;Ramlal,A;Cranston,B;Hanchard,B;Blattner,WA
通讯作者: Blattner,WA