Effects of Oolong Tea on Metabolism of Plasma Fat in Mice under Restraint Stress
Effects of Oolong Tea on Metabolism of Plasma Fat in Mice under Restraint Stress
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乌龙茶对束缚应激小鼠血浆脂肪代谢的影响
DOI：
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发表时间：
2002
期刊：
影响因子：
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通讯作者：
Takaharu Tanaka
中科院分区：
文献类型：
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作者：
H. Kurihara;H. Fukami;H. Koda;N. Tsuruoka;Namino Sugiura;H. Shibata;Takaharu Tanaka
研究了乌龙茶对束缚应激小鼠血脂基础代谢的影响。当将脂肪乳剂（Intraperid20%;含20%大豆油的脂肪乳剂）静脉注射到小鼠体内时，束缚应激使血浆甘油三酯（TG）消除的半衰期（T1/2）从28.7 min延长至55.5 min。应激小鼠的每分钟消除率为48.2%，饥饿对照小鼠的消除率为100%。因此，TG代谢被应激破坏，TG作为能量来源的使用减少。本研究发现，束缚应激对脂代谢有显著的影响。在对照应激小鼠中施用Intraperoid后35分钟，血浆TG为515.9±29.9 mg/dl，在给予咖啡因100 mg/kg体重的应激组中为478.7±26.7 mg/dl，在给予乌龙茶1000 mg/kg体重的应激组中为418.3±18.4 mg/dl，分别改善7.2%和18.9%，与未处理对照组的值相同。乌龙茶的摄入缓解了应激引起的血脂代谢率下降;这种效果可能是由于茶的某些非特异性应激缓解特性或茶中多酚等的特性加速了脂质代谢。乌龙茶对血浆TG代谢具有抗应激作用，且这种作用不依赖于咖啡因。
We investigated the effects of oolong tea on the basic metabolism of plasma lipids in mice under restraint stress. When a lipid emulsion (Intralipid 20%; a lipid emulsion containing 20% soybean oil) was injected intravenously into mice, the restraint stress prolonged the half-life (T1/2) of elimination for plasma triglyceride (TG) from 28.7 to 55.5 min. The elimination rate per minute was 48.2% in stressed mice with the rate in starved control mice as 100%. Therefore, TG metabolism was disrupted by the stress, and the use of TG as an energy source decreased. We found that the metabolism of lipids significantly response to the restrained stress in the present study. Plasma TG was 515.9±29.9 mg/dl 35 min after Intralipid administration in control stressed mice, 478.7±26.7 mg/dl in the stressed group given caffeine 100 mg/kg of body weight, and 418.3±18.4 mg/dl in the stressed group given 1000 mg/kg oolong tea, an improvement by 7.2% and 18.9%, respectively, with the value for the untreated control group. The intake of oolong tea alleviated the stress-induced decrease in the rate of blood lipid metabolism; this effect may have arisen from some nonspecific stress-relieving property of the tea or from acceleration of lipid metabolism by properties of polyphenols, etc. in tea. Oolong tea had anti-stress effects on plasma TG metabolism, and the effects did not depend on caffeine.
秋水仙碱阻断轴突运输后，促肾上腺皮质激素促分泌素释放的模式具有低血糖、新颖性和抑制性。
影响因子：
4.8
作者：
Romero,LM;Plotsky,PM;Sapolsky,RM
通讯作者：
Sapolsky,RM