L-TYROSINE3,5-3H ASSAY FOR TYROSINASE DEVELOPMENT IN SKIN OF NEWBORN HAMSTERS
L-TYROSINE3,5-3H ASSAY FOR TYROSINASE DEVELOPMENT IN SKIN OF NEWBORN HAMSTERS
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DOI：
10.1126/science.164.3881.838
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发表时间：
1969-01-01
期刊：
影响因子：
56.9
通讯作者：
POMERANTZ, SH
中科院分区：
文献类型：
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作者：
POMERANTZ, SH
仓鼠皮肤中的酪氨酸酶，通过从L-酪氨酸-3，5 - 3 H产生3 HOH来测量，从14天的胎儿到生命的第6天，其比活性增加约7倍。白化病仓鼠没有表现出任何活动，但叙利亚仓鼠的腹侧（白色）区域存在酶。需要3，4-二羟基-L-苯丙氨酸作为共底物。
Tyrosinase in hamster skin, measured by the production of3HOH from L-tyrosine-3,5-3H, increases about sevenfold in specific activity from the 14-day fetus to day 6 of life. Albino hamsters exhibit no activity, but enzyme is present in the ventral (white) areas of the Syrian hamster. 3,4-Dihydroxy-L-phenylalanine is required as a cosubstrate.