High desorption-ionization yields of large biomolecules induced by fast C-60 projectiles
High desorption-ionization yields of large biomolecules induced by fast C-60 projectiles
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DOI：
10.1016/s0168-1176(97)00057-8
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发表时间：
1997-10-01
期刊：
影响因子：
--
通讯作者：
Pautrat, M
中科院分区：
文献类型：
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作者：
Brunelle, A;DellaNegra, S;Pautrat, M
C-60分子加速到MeV能量（20 MeV）已被用于诱导固体样品中大分子的解吸-电离。对于由胰蛋白酶分子组成的样品，二级分子离子发射产率比MeV原子离子大两个数量级。这是由于20 MeV的C-60弹丸在固体中沉积了非常高的能量密度，每次撞击后都会产生大量物质。虽然飞行时间质谱可以在几秒钟内记录下来，但与其他粒子诱导解吸方法相比，它更多的是获得机理方面的知识，这是获得含能富勒烯这些初步结果的目的。(C) 1997爱思唯尔科学有限公司
C-60 molecules accelerated to MeV energies (20 MeV) have been used to induce the desorption-ionization of large bio-molecules from solid samples. For a sample consisting of trypsin molecules, the secondary molecular ion emission yield is about two orders of magnitude larger than with MeV atomic ions. This is a consequence of the very high energy density deposited in solids by 20 MeV C-60 projectiles that gives rise to a large amount of matter ejected after each impact. Although time-of-flight mass spectra can be recorded within a few seconds, it is more the acquisition of knowledge on mechanistic aspects, in comparison with other particle-induced desorption methods, which is the objective of obtaining these first results with energetic fullerenes. (C) 1997 Elsevier Science B.V.