Protein tyrosine phosphatases in the developing nervous system

Protein tyrosine phosphatases in the developing nervous system
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DOI:
10.1016/s0955-0674(98)80139-7
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发表时间:
1998-04-01
影响因子:
7.5
通讯作者:
Van Vactor, D
Van Vactor, D
中科院分区:
生物学2区
文献类型:
--
作者:
Van Vactor, D

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蛋白酪氨酸磷酸酶(PTPs)构成了一个不同的细胞内和跨膜蛋白家族。表达数据和最近的遗传分析表明,许多ptp在神经系统发育的不同方面发挥重要作用。尽管PTP机制仍然知之甚少,但目前的数据表明这些信号通路相当复杂。(C) Current Biology Ltd . ISSN 0955-0674。
Protein tyrosine phosphatases (PTPs) constitute a diverse family of intracellular and transmembrane proteins. Expression data and recent genetic analyses indicate that many PTPs play important roles in different aspects of nervous system development. Although PTP mechanisms are still poorly understood, current data suggest considerable complexity in these signaling pathways. (C) Current Biology Ltd ISSN 0955-0674.