Genome sequencing and analysis of the model grass Brachypodium distachyon
Genome sequencing and analysis of the model grass Brachypodium distachyon
复制标题
模式草短柄草基因组测序与分析
DOI：
10.1038/nature08747
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发表时间：
2010-02-11
期刊：
影响因子：
64.8
通讯作者：
Baxter, Ivan
中科院分区：
文献类型：
--
作者：
Vogel, John P.;Garvin, David F.;Baxter, Ivan
禾本科的三个亚科，草科、禾本科和禾本科，为人类提供了大量的营养，并有望成为可再生能源的主要来源。在这里，我们描述了野生草Brachypodium distachyon （Brachypodium）的基因组序列，据我们所知，这是Pooideae亚科中第一个被测序的成员。对短柄草、水稻和高粱的基因组进行比较，揭示了这些禾本科植物广泛多样性的精确基因组进化史，并为分析小麦等具有重要经济意义的类群禾本科植物的大型基因组建立了模板。高质量的基因组序列，加上易于栽培和转化，体积小，生命周期快，将有助于短柄草发挥其作为开发新能源和粮食作物的重要模式系统的潜力。
Three subfamilies of grasses, the Ehrhartoideae, Panicoideae and Pooideae, provide the bulk of human nutrition and are poised to become major sources of renewable energy. Here we describe the genome sequence of the wild grass Brachypodium distachyon (Brachypodium), which is, to our knowledge, the first member of the Pooideae subfamily to be sequenced. Comparison of the Brachypodium, rice and sorghum genomes shows a precise history of genome evolution across a broad diversity of the grasses, and establishes a template for analysis of the large genomes of economically important pooid grasses such as wheat. The high-quality genome sequence, coupled with ease of cultivation and transformation, small size and rapid life cycle, will help Brachypodium reach its potential as an important model system for developing new energy and food crops.