CORTICAL CONNECTIONS OF INFERIOR TEMPORAL AREA TEO IN MACAQUE MONKEYS
CORTICAL CONNECTIONS OF INFERIOR TEMPORAL AREA TEO IN MACAQUE MONKEYS
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DOI：
10.1002/cne.903340111
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发表时间：
1993-08-01
影响因子：
2.5
通讯作者：
UNGERLEIDER, LG
中科院分区：
文献类型：
--
作者：
DISTLER, C;BOUSSAOUD, D;UNGERLEIDER, LG
在猕猴中，病变涉及下颞叶皮层的后部，细胞结构区TEO，产生严重损害的视觉模式的歧视。最近，该区域已被证明包含对侧视野的完整但粗糙的表示（Boussaoud，Desimone和Ungerleider：J. Comp. Neurol. 306：554- 575，'91）。由于TEO区的输入和输出尚未完全描述，我们注入了各种逆行和顺行示踪剂到11个生理上确定的网站内TEO的7只恒河猴和分析其皮质connects.Our结果表明，TEO接收前馈，地形组织的输入从prestriate区V2，V3和V4的区域和层状分布。附加的稀疏前馈输入来自区域V3 A、V4 t和MT。这些输入中的每一个都由来自TEO的反馈投影进行往复。TEO还与上级颞区底部（FST区）、上级颞沟最后内侧部分的皮质（后顶叶沟区[PP区]）、顶内沟皮质（包括外侧顶内区[LIP区]）、额叶视野和海马旁回TF区之间存在交互中间型联系。与V3 A，V4 t，和PP的连接被发现后，才在周边领域表示的TEO注射。最后，发现TEO以前馈模式投射到TE区和上级颞沟的外侧岸和底部上的FST前的区域（区域TEm、TEa和IPa，Seltzer和Pandya：Brain Res.149：1-24，'78），所有这些都向TEO发送反馈投射。反馈预测也出现在海马旁区TH和TG区，36，可能35。这些都是补充只有稀疏前馈投影TG从中央场表示在TEO和TH从周边领域representations. Results的结果表明，TEO形成了一个重要的环节，在枕颞通路的对象识别，发送视觉信息向前从V1和前纹状体中继V2-V4的前下颞区TE。 (C)1993年Wiley-Liss，Inc.*
In macaque monkeys, lesions involving the posterior portion of the inferior temporal cortex, cytoarchitectonic area TEO, produce a severe impairment in visual pattern discrimination. Recently, this area has been shown to contain a complete, though coarse, representation of the contralateral visual field (Boussaoud, Desimone, and Ungerleider: J. Comp. Neurol. 306:554--575, '91). Because the inputs and outputs of area TEO have not yet been fully described, we injected a variety of retrograde and anterograde tracers into 11 physiologically identified sites within TEO of seven rhesus monkeys and analyzed the areal and laminar distribution of its cortical connections.Our results show that TEO receives feedforward, topographically organized inputs from prestriate areas V2, V3, and V4. Additional sparser feedforward inputs arise from areas V3A, V4t, and MT. Each of these inputs is reciprocated by a feedback projection from TEO. TEO was also found to have reciprocal intermediate-type connections with the fundus of the superior temporal area (area FST), cortex in the most posteromedial portion of the superior temporal sulcus (the posterior parietal sulcal zone [area PP]), cortex in the intraparietal sulcus (including the lateral intraparietal area [area LIP]), the frontal eye field, and area TF on the parahippocampal gyrus. The connections with V3A, V4t, and PP were found only after injections in the peripheral field representations of TEO. Finally, TEO was found to project in a feedforward pattern to area TE and to areas anterior to FST on the lateral bank and floor of the superior temporal sulcus (areas TEm, TEa, and IPa, Seltzer and Pandya: Brain Res. 149:1-24, '78), all of which send feedback projections to TEO. Feedback projections also arise from parahippocampal area TH, and areas TG, 36, and possibly 35. These are complemented by only sparse feedforward projections to TG from central field representations in TEO and to TH from peripheral field representations.The results thus indicate that TEO forms an important link in the occipitotemporal pathway for object recognition, sending visual information forward from V1 and prestriate relays in V2-V4 to anterior inferior temporal area TE. (C) 1993 Wiley-Liss, Inc.*