Chlorhexidine and hypersensitivity reactions in dentistry

Chlorhexidine and hypersensitivity reactions in dentistry
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DOI:
10.1038/sj.bdj.2012.1086
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发表时间:
2012-12-01
影响因子:
2.6
通讯作者:
Gibson, J.
Gibson, J.
中科院分区:
医学4区
文献类型:
--
作者:
Pemberton, M. N.;Gibson, J.

文献摘要

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对洗必泰的免疫反应,包括过敏(I型超敏反应)和过敏性接触性皮炎/口腔炎(IV型超敏反应),已经被认识到很多年了。然而,这一潜在的安全问题在牙科领域并不广为人知。这篇论文的目的是提醒牙医和牙科护理专业人员注意洗必泰引起超敏反应的可能性,并考虑如果发生不明原因的超敏反应的可能性。
Immunological reactions to chlorhexidine, including allergy (Type I hypersensitivity) and allergic contact dermatitis/stomatitis (Type IV hypersensitivity), have been recognised for many years. This potential safety issue, however, is not well known within dentistry. The purpose of this paper is to alert dentists and dental care professionals to the potential of chlorhexidine in causing hypersensitivity reactions and to consider this possibility if unexplained hypersensitivity reactions occur.