Fluoride-containing bioactive glass-ceramics
Fluoride-containing bioactive glass-ceramics
复制标题
DOI：
10.1016/j.jnoncrysol.2012.03.014
复制
发表时间：
2012-07-01
影响因子：
3.5
通讯作者：
Hill, R. G.
中科院分区：
文献类型：
--
作者：
Brauer, D. S.;Anjum, M. N.;Hill, R. G.
氟磷灰石玻璃陶瓷具有骨传导性。并且在生物活性硅酸盐玻璃基质中含有氟磷灰石晶体的玻璃-陶瓷可将氟磷灰石的益处与生物活性玻璃的骨再生性质联合收割机结合。采用熔融急冷法制备了高磷含量（约6mol%P2O5）的SiO2-P2 O 5-CaO-Na 2 O-CaF 2生物活性玻璃。使用密度测量和计算的结构研究证实了磷作为正磷酸盐的存在。在热处理时，玻璃结晶成混合的氟化钠正磷酸盐（含钠组合物）和氟磷灰石（不含钠组合物）。氟化物抑制自发结晶，允许通过受控结晶形成玻璃陶瓷。一个显着的特点是，硅酸盐网络聚合和网络连接在结晶过程中没有改变，导致正磷酸盐和氟磷灰石晶体嵌入在生物活性玻璃基质。通过保持高磷酸盐含量和低钠含量，可以获得氟磷灰石玻璃陶瓷，同时不影响生物活性硅酸盐玻璃相的结构。(C)2012爱思唯尔有限公司版权所有。
Fluorapatite glass-ceramics are osteoconductive. and glass-ceramics containing fluorapatite crystals in a bioactive silicate glass matrix can combine the benefits of fluorapatite with the bone-regenerative properties of bioactive glasses. High phosphate content (around 6 mol% P2O5) bioactive glasses (SiO2-P2O5-CaO-Na2O-CaF2) were prepared by a melt-quench route. Structural investigation using density measurements and calculations confirmed the presence of phosphorus as orthophosphate. Upon heat treatment, the glasses crystallised to mixed sodium calcium fluoride orthophosphates (sodium-containing compositions) and fluorapatite (sodium-free composition). Fluoride suppressed spontaneous crystallisation, allowing formation of glass-ceramics by controlled crystallisation. A notable feature is that silicate network polymerisation and network connectivity did not change during crystallisation, resulting in orthophosphate and fluorapatite crystals embedded within a bioactive glass matrix. By keeping the phosphate content high and the sodium content low, fluorapatite glass-ceramics can be obtained, while not affecting the structure of the bioactive silicate glass phase. (C) 2012 Elsevier B.V. All rights reserved.