In-vitro antimicrobial susceptibility of the 'Streptococcus milleri' group (Streptococcus anginosus, Streptococcus constellatus and Streptococcus intermedius)
In-vitro antimicrobial susceptibility of the 'Streptococcus milleri' group (Streptococcus anginosus, Streptococcus constellatus and Streptococcus intermedius)
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DOI：
10.1093/jac/37.2.371
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发表时间：
1996-02-01
影响因子：
5.2
通讯作者：
Stobberingh, EE
中科院分区：
文献类型：
--
作者：
Jacobs, JA;Stobberingh, EE
收集了423株临床分离的米勒链球菌，并进行了对12种抗生素的敏感性试验。只有1.4%的菌株对青霉素中度敏感。所有菌株均未表现出对庆大霉素的高度耐药。对红霉素、罗红霉素和克林霉素的耐药率分别为2.6%、2.4%和2.4%。耐多西环素的菌株占5.7%，以血管紧张素转换链球菌最多见。所有菌株对头孢噻肟、万古霉素和替考拉宁敏感。这项研究的结果没有表明‘米勒链球菌’菌株的抗生素耐药性发生了变化，但可能会出现局部的抗生素敏感性差异。
A collection of 423 clinical 'Streptococcus milleri' strains was speciated and tested for susceptibilities to twelve antibiotics. Only 1.4% of the strains were of intermediate susceptibility to penicillin. None of the strains exhibited high-level resistance to gentamicin. Strains resistant to erythromycin, roxithromycin and clindamycin were found with a frequency of 2.6%, 2.4% and 2.4% respectively. Doxycycline resistance was found in 5.7% of the strains and occurred most frequently in Streptococcus anginosus. All the strains were susceptible to cefotaxime, vancomycin and teicoplanin. The results of this study do not indicate changing antibiotic resistance in strains of the 'S. milleri' group, but local differences in antibiotic susceptibilities may occur.