Drug and family therapy in the aftercare of acute schizophrenics.
Drug and family therapy in the aftercare of acute schizophrenics.
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急性精神分裂症患者善后护理中的药物和家庭治疗。
DOI：
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发表时间：
1978
影响因子：
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通讯作者：
M. Steinberg
中科院分区：
文献类型：
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作者：
M. Goldstein;E. Rodnick;J. Evans;P. May;M. Steinberg
经过短暂的住院治疗，104名急性，年轻的精神分裂症患者，分层的病前调整，随机分配到一个为期六周的对照试验的四个善后条件。条件涉及两种剂量水平的庚酸氟奋乃静（1毫升或0.25毫升）和存在或不存在的危机导向的家庭治疗。在6周期间和6个月随访时，接受高剂量和家庭治疗的患者复发率最低（0%），而低剂量无治疗组复发率最高（48%）。简明精神病评定量表症状评级揭示了一个显着的家庭治疗效果，在六个月内持续只有治疗患者最初接受高剂量的药物。许多相互作用，发现发病前的调整状态和两种治疗条件的反应。
After a brief inpatient hospitalization, 104 acute, young schizophrenics, stratified by premorbid adjustment, were randomly assigned to one of four aftercare conditions for a six-week controlled trial. Conditions involved one of two dose levels of fluphenazine enanthate (1 ml or 0.25 ml) and presence or absence of crisis-oriented family therapy. Relapses during the six-week period and at six-month follow-up were least in patients who received both high-dose and family therapy (0%) and greatest (48%) in the low-dose-no therapy group. Brief Psychiatric Rating Scale symptom ratings disclosed a significant family therapy effect at six weeks that was sustained at six months only for therapy patients originally receiving the high drug dose. Numerous interactions were found between premorbid adjustment status and response to the two treatment conditions.