Multilevel regulation of growth rate in yeast revealed using systems biology.
Multilevel regulation of growth rate in yeast revealed using systems biology.
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DOI：
10.1186/jbiol56
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发表时间：
2007
影响因子：
--
通讯作者：
Schreiber SL
中科院分区：
文献类型：
--
作者：
Ramanathan A;Schreiber SL
改变生长速率对转录组、蛋白质组和代谢组的影响已被系统地研究。在不同的营养条件下进行的测量，对应于主要与生长速率相关的生化途径，揭示了线粒体代谢和TOR（雷帕霉素靶点）信号通路的核心作用。
The effect of changing growth rates on the transcriptome, proteome and metabolome has been systematically studied. Measurements made under varying nutrient conditions, corresponding to biochemical pathways that correlate primarily with growth rate, reveal a central role for mitochondrial metabolism and the TOR (target of rapamycin) signaling pathway.