DEPRESSED MOTHERS AS INFORMANTS IN FAMILY HISTORY RESEARCH - ARE THEY ACCURATE
DEPRESSED MOTHERS AS INFORMANTS IN FAMILY HISTORY RESEARCH - ARE THEY ACCURATE
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DOI：
10.1016/0165-1781(88)90115-1
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发表时间：
1988-06-01
影响因子：
11.3
通讯作者：
PRABUCKI, K
中科院分区：
文献类型：
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作者：
BRESLAU, N;DAVIS, GC;PRABUCKI, K
研究人员以333对母子为样本，研究了母亲重度抑郁症与儿童症状之间的关系。基于儿童自我报告的研究结果与基于母亲关于孩子的报告的研究结果进行了比较。儿童数据支持抑郁症特有的传播。相比之下，母亲的数据显示，研究中涵盖的所有精神症状（包括抑郁、焦虑、对立、注意力不集中、多动、冲动和反社会行为）的风险都有所增加。多变量分析的结果支持这样的假设，即母亲和孩子之间的差异在一定程度上是抑郁的母亲倾向于认为自己的孩子更有症状的结果。如果受影响的先证者患有严重抑郁症或抑郁症状，则使用先证者作为举报人可能导致对家族聚集性的高估。
A sample of 333 mother-child dyads was used to examine the association between major depression in mothers and children's symptoms. Findings based on children's self-reports were compared to findings based on mothers' reports about the children. Children's data support a depression-specific transmission. In contrast, mothers' data show an increased risk forallpsychiatric syndromes covered in the study (including depression, anxiety, oppositionalism, inattention, hyperactivity, impulsivity, and antisocial acts). Results from multivariate analysis support the hypothesis that the discrepancy between mothers and children is in part a function of the tendency of depressed mothers to view their children as more symptomatic. The use of probands as informants may lead to an overestimation of familial aggregation, if the affected probands suffer from major depression or depressive symptoms.