EFFECT OF THE SHORT EAR GENE ON NUMBER OF RIBS AND PRESACRAL VERTEBRAE IN THE HOUSE MOUSE
EFFECT OF THE SHORT EAR GENE ON NUMBER OF RIBS AND PRESACRAL VERTEBRAE IN THE HOUSE MOUSE
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DOI：
10.1086/281482
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发表时间：
1946-01-01
影响因子：
2.9
通讯作者：
GREEN, MC
中科院分区：
文献类型：
--
作者：
GREEN, EL;GREEN, MC
为研究小家鼠短耳基因的多重效应，建立了5个正常短耳强制杂合的近交系（Sese × Sese），并通过兄妹交配保持。5个品系中有两个品系在近交10代后仍存活，其中一个品系具有检测短穗基因效应的适当遗传组成。在这一个品系中，短穗基因，或含有短穗基因但没有其他可识别基因的一小段染色体，倾向于减少肋骨对的数量。这一效应得到了所有5个品系早期近交世代的证据的证实，并且与肋骨生产的一般水平无关。短耳基因对骶前椎骨的数量没有影响。
For studying the multiple effects of the short ear gene in the house mouse, Mus musculus, 5 inbred strains with forced heterozygosis for normal and short ear (Sese X sese) were established and maintained by brother-by-sister matings. Two of the 5 strains have survived beyond the 10th generation of inbreeding, and one of these has the appropriate genetic constitution for detecting the effects of the short ear gene. In this one strain the short ear gene, or a small segment of chromosome which contains it but no other recognizable genes, tends to reduce the number of pairs of ribs. This effect is confirmed by evidence from the early inbred generations of all 5 strains and is independent of the general level of rib production. The short ear gene has no effect on the number of presacral vertebrae.