The rate of decline in resistance to anoxia of rabbits, dogs and guinea pigs from the onset of viability to adult life
The rate of decline in resistance to anoxia of rabbits, dogs and guinea pigs from the onset of viability to adult life
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DOI：
10.1152/ajplegacy.1944.140.5.609
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发表时间：
1944-02-01
影响因子：
--
通讯作者：
Webster, E
中科院分区：
文献类型：
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作者：
Glass, HG;Snyder, FF;Webster, E
本研究旨在确定新生兔、狗和豚鼠在呼吸氮气而不是空气时能存活多久。胚胎学家很早就认识到，在缺氧的情况下，胎儿的存活时间比在类似情况下的母亲长。以前的一些调查特别令人感兴趣。1813年，勒·加洛瓦（Le Gallois）注意到，新生兔子在断头后，呼吸运动持续15分钟;在溺水窒息时，持续27分钟;在开胸后，持续30分钟;在心脏摘除后，持续20分钟。出生后30天，发现了成人类型的反应，呼吸在2分钟内停止。Paul Bert（2）观察到新生大鼠在浸入水中30分钟期间呼吸运动的持续性。出生后20天，呼吸在约1+分钟内停止。他还注意到，猫窝伴侣在20度的水中存活了26分钟，而在3G度的水中存活时间仅为11#分钟。
The present investigation was undertaken to determine how long newborn rabbits, dogs and guinea pigs can survive when breathing nitrogen instead of air. Embryologists have long recognized the fact that when deprived of oxygen, the tetus survived longer than the mother under similar circumstances. Certain previous investigations are of special interest. Le Gallois (l), in 1813, noted that in newborn rabbits, following decapitation, respiratory movements persisted for 15 minutes; in asphyxia by submersion, 27 minutes; after opening the thorax, 30 minutes; and following extirpation of the heart, 20 minutes. Thirty days after birth, the adult type of response was found and respiration ceased within 2 minutes.Paul Bert (2) observed in newborn rats the persistence of respiratory movements for 30 minutes during submersion in water. Twenty days after birth, respiration ceased in about l+ minutes. He also noted that cat litter mates submerged in water at 20 degrees survived 26 minutes, while at 3G degrees the time of survival was only ll# minutes.