Season of birth is associated with anthropometric and neurocognitive outcomes during infancy and childhood in a general population birth cohort
Season of birth is associated with anthropometric and neurocognitive outcomes during infancy and childhood in a general population birth cohort
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DOI：
10.1016/j.schres.2005.07.017
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发表时间：
2006-01-01
影响因子：
4.5
通讯作者：
Buka, S
中科院分区：
文献类型：
--
作者：
McGrath, JJ;Saha, S;Buka, S
“出生季节”效应是精神分裂症流行病学中最常被重复的关联之一。相比之下，在一般人群中，出生季节和发育之间的关系却相对知之甚少。本研究的目的是在一个以社区为基础的大型出生队列中，探讨出生季节对从出生到7岁的各种人体测量和神经认知变量的影响。从美国围产期合作项目中抽取了37周后出生的白人单胎婴儿样本（n = 22123）。在出生、8个月、4岁和7岁时评估人体测量变量（体重、头围、长/高）和各种神经认知发展指标。与夏/秋出生的婴儿相比，冬/春出生的婴儿出生时明显更长，7岁时明显更重、更高、头围更大。冬季/春季出生的婴儿在8个月时的Bayley运动评分、4岁时的Graham-Ernhart Block测试、7岁时的韦氏智力表现和全量表得分显著较高，但在7岁时的Bender-Gestalt测试得分显著较低。冬季/春季出生虽然与精神分裂症风险增加有关，但通常与身体和认知发育方面的较好结果相关。(c) 2005 Elsevier B.V.版权所有
The 'season of birth' effect is one of the most consistently replicated associations in schizophrenia epidemiology. In contrast, the association between season of birth and development in the general Population is relatively poorly understood. The aim of this study was to explore the impact of season of birth on various anthropometric and neurocognitive variables from birth to age seven in a large, community-based birth cohort. A sample of white singleton infants born after 37 weeks gestation (n =22,123) was drawn from the US Collaborative Perinatal Project. Anthropometric variables (weight, head circumference, length/height) and various measures of neurocognitive development, were assessed at birth, 8 months, 4 and 7 years of age. Compared to surnmer/autumn born infants, winter/spring born infants were significantly longer at birth, and at age seven were significantly heavier, taller and had larger head circumference. Winter/spring born infants were achieving significantly higher scores on the Bayley Motor Score at 8 months, the Graham-Ernhart Block Test at age 4, the Wechsler Intelligence Performance and Full Scale scores at age 7, but had significantly lower scores on the Bender-Gestalt Test at age 7 years. Winter/spring birth, while associated with an increased risk of schizophrenia, is generally associated with superior outcomes with respect to physical and cognitive development. (c) 2005 Elsevier B.V. All rights reserved.