Antral myoelectric activity, gastric emptying, and dyspeptic symptoms in diabetics
Antral myoelectric activity, gastric emptying, and dyspeptic symptoms in diabetics
复制标题
DOI：
10.3109/00365529509101626
复制
发表时间：
1995-12-01
影响因子：
1.9
通讯作者：
Ricken, D
中科院分区：
文献类型：
--
作者：
Pfaffenbach, B;Wegener, M;Ricken, D
背景：胃电描记(EGG)使皮肤测量胃电活动成为可能。电异常和胃肠动力障碍之间的关系已经被证明。这项研究的主要目的是调查是否可以通过胃电预测糖尿病胃轻瘫。方法：对18例胰岛素治疗的2型糖尿病慢性消化不良患者进行胃电生理检查，其中女性9例，男性9例，年龄45~76岁，年龄中位数。禁食一夜后，在禁食1h和进食液固试验餐(370kcal；0.5mCi-99m-胶体标记的液体)后1h，用放置在胃窦上方皮肤上的一对电极超声捕捉胃窦电活动。几个胃电参数包括主频(DF)、DF在正常范围内的百分比(2~4次/分钟(CPM))、胃动过缓(0.05)。此外，有胃排空障碍的糖尿病患者的胃电图值(约40%)与没有胃轻瘫的糖尿病患者的数据没有差别。此外，尽管消化不良与放射性核素显着相关，但与胃电检查没有发现相关性。结论：胃电图似乎不适合于评估II型糖尿病患者的运动障碍。
Background: Electrogastrography (EGG) enables the cutaneous measurement of gastric electric activity. An association between electric abnormalities and gastrointestinal motility disorders has been shown. The primary objective of this study was to investigate whether diabetic gastroparesis could be predicted by EGG. Methods: EGG was performed in 18 insulin-treated type-II diabetics (9 female, 9 male; median age, 64 years; range, 45-76 years) with chronic dyspepsia. After an overnight fast, during 1 h in the fasting and 1 h in the fed state after ingestion of a liquid-solid test meal (370 kcal; liquid phase labeled with 0.5 mCi Tc-99m-colloid) antral electric activity was captured by one pair of electrodes sonographically placed on the skin overlying the gastric antrum. Several EGG variables including dominant frequency (DF), percentages of DF in the normal range (2-4 cycles per minute (cpm)), bradygastria ( 0.05). Moreover, the EGG values in diabetics with delayed gastric emptying (about 40%) did not differ from data in diabetics without gastroparesis. Furthermore, whereas dyspepsia correlated significantly with radioscintigraphy, no correlation with EGG could be found. Conclusions: Electrogastrography seems to be unsuitable for assessment of motility disorders in type-II diabetics.