Carinatumins A-C, new alkaloids from Lycopodium carinatum inhibiting acetylcholinesterase
Carinatumins A-C, new alkaloids from Lycopodium carinatum inhibiting acetylcholinesterase
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DOI：
10.1016/j.bmc.2006.12.005
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发表时间：
2007-02-15
影响因子：
3.5
通讯作者：
Morita, Hiroshi
中科院分区：
文献类型：
--
作者：
Choo, Chee Yan;Hirasawa, Yusuke;Morita, Hiroshi
从石松石松中分离出三种新的石松生物碱，carinaturnins A-C (1-3)。基于2D NMR相关性阐明了1-3的结构和立体化学。 Carinatumins A (1) 和 B (2) 对乙酰胆碱酯酶表现出有效的抑制活性。 (c) 2006 Elsevier Ltd. 保留所有权利。
Three new Lycopodium alkaloids, carinaturnins A-C (1-3), have been isolated from the club moss Lycopodium carinatum. Structures and stereochemistry of 1-3 were elucidated on the basis of 2D NMR correlations. Carinatumins A (1) and B (2) exhibited a potent inhibitory activity against acetylcholinesterase. (c) 2006 Elsevier Ltd. All rights reserved.