AFFERENT-PROJECTIONS TO CENTRAL NUCLEUS OF INFERIOR COLLICULUS IN RAT
AFFERENT-PROJECTIONS TO CENTRAL NUCLEUS OF INFERIOR COLLICULUS IN RAT
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DOI：
10.1016/0006-8993(78)90858-2
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发表时间：
1978-01-01
期刊：
影响因子：
2.9
通讯作者：
BEYERL, BD
中科院分区：
文献类型：
--
作者：
BEYERL, BD
采用辣根过氧化物酶（HRP）逆行转运的方法研究了大鼠下丘的传入投射。向中央核注射大量HRP后，耳蜗核内的细胞、上橄榄复合体和听觉皮层被染色。在对侧耳蜗背核内，梭状细胞被大量标记。巨细胞也被标记在更深的层。在对侧耳蜗腹侧核中，几乎所有的主要细胞类型都被标记，其中一些类型被标记的数量多于其他类型。耳蜗腹侧核（PVCN）后腹侧分裂章鱼细胞未被标记。同侧和对侧侧橄榄核外侧上核（LSO）、同侧橄榄核内侧上核（MSO）、同侧和对侧梯形体外侧核（LTB）、同侧梯形体腹侧核（VTB）和同侧上橄榄旁核（SPN）均有hrp阳性细胞。听觉皮层第五层锥体细胞被大量标记。向中央核注射少量HRP可在耳蜗核、上橄榄复合体和听觉皮层的有限区域内产生标记细胞。注射到中央核的背侧区域导致细胞标记在耳蜗背核和耳蜗腹侧核的腹侧区域，以及LSO的外侧区域。这些区域包含的神经元被认为具有较低的最佳频率。在中央核更多的腹侧区域注射导致更多的耳蜗核背侧区域和更多的LSO内侧区域的细胞标记，这与这些结构内的张力局部进展一致。
The afferent projections to the inferior colliculus of the rat were studied using the method of retrograde transport of horseradish peroxidase (HRP). Following large injections of HRP into the central nucleus, cells within the cochlear nuclei, superior olivary complex and auditory cortex were stained. Within the contralateral dorsal cochlear nucleus, fusiform cells were heavily labeled. Giant cells were also labeled in deeper layers. In the contralateral ventral cochlear nucleus, virtually all major cell types were labeled, with some types being labeled in greater numbers than others. Octopus cells of posteroventral division of ventral cochlear nucleus (PVCN) were never labeled. HRP-positive cells were found in ipsilateral and contralateral lateral superior olivary nucleus (LSO), ipsilateral medial superior olivary nucleus (MSO), ipsilateral and contralateral lateral nucleus of the trapezoid body (LTB), ipsilateral ventral nucleus of the trapezoid body (VTB) and ipsilateral superior paraolivary nucleus (SPN). Pyramidal cells of layer V of auditory cortex were heavily labeled. Small injections of HRP into the central nucleus resulted in labeled cells within restricted regions of the cochlear nuclei, superior olivary complex and auditory cortex. Injections into dorsal regions of the central nucleus resulted in cells labeled in ventral regions of the dorsal and ventral cochlear nuclei, and in lateral regions of LSO. These regions contain neurons which are considered to have low best frequencies. Injections placed in more ventral regions of the central nucleus led to labeling of cells in more dorsal regions of the cochlear nuclei and more medial regions of LSO in agreement with the tonotopical progressions within these structures.