Temporal trends in cardiogenic shock complicating acute myocardial infarction
Temporal trends in cardiogenic shock complicating acute myocardial infarction
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DOI：
10.1056/nejm199904153401504
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发表时间：
1999-04-15
影响因子：
158.5
通讯作者：
Gore, JM
中科院分区：
文献类型：
--
作者：
Goldberg, RJ;Samad, NA;Gore, JM
背景关于急性心肌梗死并发心源性休克的发生率和死亡率的趋势，可获得的信息有限。我们研究了1975-1997年间单一社区心源性休克并发急性心肌梗死的发生率和住院死亡率。方法对1975-1997年间在马萨诸塞州伍斯特大都会医院住院确诊的9076名急性心肌梗死患者进行观察研究。结果急性心肌梗死患者心源性休克的发生率随时间保持相对稳定，平均为7.1%。多变量回归分析的结果表明，最近几年住院的患者发生休克的风险并不比1970年代中后期住院的患者低很多。发生心源性休克的患者住院期间死亡的风险(71.7%)显著高于未发生心源性休克的患者(12.0%，P
Background Limited information is available on trends in the incidence of and mortality due to cardiogenic shock complicating acute myocardial infarction. We studied the incidence of cardiogenic shock complicating acute myocardial infarction and in-hospital death rates among patients with this condition in a single community from 1975 through 1997.Methods We conducted an observational study of 9076 residents of metropolitan Worcester, Massachusetts, who were hospitalized with confirmed acute myocardial infarction in all local hospitals during 11 one-year periods between 1975 and 1997. Our study included periods before and after the advent of reperfusion therapy.Results The incidence of cardiogenic shock remained relatively stable over time, averaging 7.1 percent among patients with acute myocardial infarction. The results of a multivariable regression analysis indicated that the patients hospitalized during recent study years were not at a substantially lower risk for shock than patients hospitalized in the mid-to-late 1970s. Patients in whom cardiogenic shock developed had a significantly greater risk of dying during hospitalization (71.7 percent) than those who did not have cardiogenic shock (12.0 percent, P