Biomagnetism using SQUIDs: status and perspectives
Biomagnetism using SQUIDs: status and perspectives
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DOI：
10.1088/0953-2048/19/3/024
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发表时间：
2006-03-01
影响因子：
3.6
通讯作者：
Braginski, AI
中科院分区：
文献类型：
--
作者：
Sternickel, K;Braginski, AI
生物磁学涉及测量和分析活着的生物体和人类各种器官的非常微弱的局部磁场。这样的场可以是生理起源的，也可以是由于磁性杂质或标记引起的。本文综述了生物磁学在临床研究和医学诊断中的应用现状和前景。目前，此类应用需要灵敏的磁SQUID传感器和放大器。生物磁学方法的实用性尤其取决于抑制主要环境电磁噪声的技术，以及合适的近乎实时的数据处理和解释方法。在众多的生物磁学方法和应用中，只有对人脑的功能研究(脑磁图)和肝脏磁感度测量在临床上使用，而对人体心脏的功能诊断(心磁图)接近临床接受的门槛。未来特别有希望的是正在进行的使用鱿鱼进行低场磁共振解剖成像的研究。
Biomagnetism involves the measurement and analysis of very weak local magnetic fields of living organisms and various organs in humans. Such fields can be of physiological origin or due to magnetic impurities or markers. This paper reviews existing and prospective applications of biomagnetism in clinical research and medical diagnostics. Currently, such applications require sensitive magnetic SQUID sensors and amplifiers. The practicality of biomagnetic methods depends especially on techniques for suppressing the dominant environmental electromagnetic noise, and on suitable nearly real-time data processing and interpretation methods. Of the many biomagnetic methods and applications, only the functional studies of the human brain (magnetoencephalography) and liver susceptometry are in clinical use, while functional diagnostics of the human heart (magnetocardiography) approaches the threshold of clinical acceptance. Particularly promising for the future is the ongoing research into low-field magnetic resonance anatomical imaging using SQUIDS.