Molecular clock for dating of divergence between animal phyla
Molecular clock for dating of divergence between animal phyla
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DOI：
10.1266/jjg.70.687
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发表时间：
1995-12-01
期刊：
影响因子：
--
通讯作者：
Miyata, T
中科院分区：
文献类型：
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作者：
Iwabe, N;Kuma, K;Miyata, T
为了估计缺乏化石数据的动物门的大致分化时间，重要的是要找到一个分子，在覆盖整个动物门的广泛进化距离上以近似恒定的速率进化。为此，对20种蛋白质的进化速率常数进行了研究。研究发现，不仅在不同种类的脊椎动物中，而且在脊椎动物和节肢动物之间，参与糖醇解途径的四种蛋白质，尤其是醛缩酶C的进化速度几乎是恒定的。醛缩酶C的进化速率（=0.26X10(-9)/位点/年）很可能在动物和植物之间基本保持不变。
To estimate approximate times of divergence of animal phyla lacking fossil data, it is important to find a molecule that evolves with an approximately constant rate over a wide evolutionary distance covering the whole animal phyla. For this purpose, the evolutionary rate constancy has been examined for 20 proteins. It was found that four proteins, particularly the aldolase C, involved in the glycolitic pathway, had evolved with rates that are approximately constant not only among different classes of vertebrates, but also between vertebrates and arthropods. The evolutionary rate (=0.26X10(-9)/site/year) of the aldolase C is likely to have remained essentially unchanged even between animals and plants.