Standing and Mortality in a Prospective Cohort of Canadian Adults
Standing and Mortality in a Prospective Cohort of Canadian Adults
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DOI：
10.1249/mss.0000000000000198
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发表时间：
2014-05-01
期刊：
影响因子：
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通讯作者：
Katzmarzyk, Peter T.
中科院分区：
文献类型：
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作者：
Katzmarzyk, Peter T.
研究目的一些研究已经证明久坐行为如坐着或看电视与过早死亡之间存在显著的关联。然而，死亡率和其他低能量消耗活动（如站立）之间的联系尚未得到探讨。本研究的目的是研究16,586名18-90岁加拿大成年人每日站立时间与死亡率之间的关系。方法在1981年加拿大健康调查的基线收集了关于自我报告的站立时间以及几个协变量（包括吸烟、饮酒、体力活动准备和中度至剧烈体力活动）的信息。参与者平均随访12.0年，以确定死亡状况。结果队列中有1785例死亡（743例死于心血管疾病[CVD]，530例死于癌症，512例死于其他原因）。在调整了年龄、性别和其他协变量后，站立时间与所有原因、心血管疾病和其他原因的死亡率呈负相关。在连续较高的每日站立分类中，全因死亡率的多变量校正风险比分别为1.00、0.79、0.79、0.73和0.67（P趋势
Purpose Several studies have documented significant associations between sedentary behaviors such as sitting or television viewing and premature mortality. However, the associations between mortality and other low-energy-expenditure activities such as standing have not been explored. The purpose of this study was to examine the association between daily standing time and mortality among 16,586 Canadian adults 18-90 yr of age. Methods Information on self-reported time spent standing as well as several covariates including smoking, alcohol consumption, physical activity readiness, and moderate-to-vigorous physical activity was collected at baseline in the 1981 Canada Fitness Survey. Participants were followed for an average of 12.0 yr for the ascertainment of mortality status. Results There were 1785 deaths (743 from cardiovascular disease [CVD], 530 from cancer, and 512 from other causes) in the cohort. After adjusting for age, sex, and additional covariates, time spent standing was negatively related to mortality rates from all causes, CVD, and other causes. Across successively higher categories of daily standing, the multivariable-adjusted hazard ratios were 1.00, 0.79, 0.79, 0.73, and 0.67 for all-cause mortality (P for trend