Prevalence and predictors of trichomonas infection in newly incarcerated women.
Prevalence and predictors of trichomonas infection in newly incarcerated women.
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新入狱女性滴虫感染的患病率和预测因素。
DOI：
10.1097/olq.0b013e31826e8847
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发表时间：
2012
影响因子：
3.1
通讯作者：
Clarke,JenniferG
中科院分区：
文献类型：
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作者：
Nijhawan,AnkE;Chapin,KimberleC;Salloway,Rachel;Andrea,Sarah;Champion,Jessi;Roberts,Mary;Clarke,JenniferG
阴道毛滴虫是美国最常见的可治愈的性传播感染，可导致早产、不孕和增加HIV传播。被监禁的妇女可能是在特别高的感染风险，虽然很少有研究探讨了毛滴虫感染的常规筛查在这population.MethodsWomen年龄超过18岁进入罗得岛惩教署2009年9月至2011年5月招募参加。所有妇女提交了一个自我收集的阴道拭子APTIMA转录介导的扩增检测。每个参与者都完成了一项调查，解决人口统计学，症状，性行为和物质使用的音频计算机辅助自我采访。数据分析采用多因素Logistic回归分析在SAS.ResultsData为387名妇女进行了分析。平均年龄为30岁，60%为白色，18%为西班牙裔，10%为黑人，12%为其他种族/民族。44%的人报告阴道症状，77%的人报告在监禁前30天内使用非法药物和/或大量酒精。根据APTIMA，毛滴虫的患病率为14%。感染的最强预测因素包括黑人（比值比[OR]，5.1; 95%置信区间[CI]，1.9-13.4; P< 0.01），距上次巴氏试验超过1年（OR，2.5; 95%CI，1.3-4.8; P< 0.01）和存在阴道症状（OR，2.3; 95% CI，1.2-4.7; P= 0.02）。结论滴虫感染在监禁妇女中很常见，尤其是黑人妇女，有阴道症状的妇女，以及那些没有接受常规妇科护理的人。在高危人群中筛查毛滴虫感染，特别是如果使用高灵敏度的方法，如转录介导的扩增，可能会导致增加检测和治疗。
BackgroundTrichomonas vaginalis is the most prevalent curable sexually transmitted infection in the United States and may lead to preterm delivery, infertility, and increased HIV transmission. Incarcerated women may be at especially high risk for infection, although few studies have examined routine screening for Trichomonas infection in this population.MethodsWomen older than 18 years entering the Rhode Island Department of Corrections between September 2009 and May 2011 were recruited to participate. All women submitted a self-collected vaginal swab for APTIMA transcription-mediated amplification testing. Each participant completed a survey addressing demographics, symptoms, sexual behavior, and substance use by audio computer-assisted self-interview. Data analysis was completed using multivariate logistic regression in SAS.ResultsData for 387 women were analyzed. The mean age was 30 years, 60% were white, 18% were Hispanic, 10% were black, and 12% had other race/ethnicity. Forty-four percent reported vaginal symptoms, and 77% reported illicit drug and/or heavy alcohol use in the 30 days before incarceration. The prevalence of Trichomonas was 14% by APTIMA. The strongest predictors of infection included black race (odds ratio [OR], 5.1; 95% confidence interval [CI], 1.9–13.4; P< 0.01), more than 1 year since last Papanicolaou test (OR, 2.5; 95% CI, 1.3–4.8; P< 0.01) and presence of vaginal symptoms (OR, 2.3; 95% CI, 1.2–4.7; P= 0.02).ConclusionsTrichomonas infection is common in incarcerated women, especially among black women, women with vaginal symptoms, and those not receiving routine gynecologic care. Screening for Trichomonas infection in high-risk populations, particularly if using highly sensitive methods such as transcription-mediated amplification, may lead to increased detection and treatment.