Dorsal onlay augmentation urethroplasty with small intestinal submucosa: Modified Barbagli technique for strictures of the bulbar urethra
Dorsal onlay augmentation urethroplasty with small intestinal submucosa: Modified Barbagli technique for strictures of the bulbar urethra
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DOI：
10.1111/j.1442-2042.2006.01587.x
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发表时间：
2006-11-01
影响因子：
2.6
通讯作者：
Panchev, Petar K.
中科院分区：
文献类型：
--
作者：
Donkov, Ivo I.;Bashir, Azmat;Panchev, Petar K.
目的：目的：介绍应用小肠黏膜下层（SIS）行尿道扩张术治疗球尿道狭窄的临床经验。方法：对9例尿道狭窄4- 6cm的男性患者行尿道扩张术。所有患者均通过病史、体格检查、逆行尿道造影和尿流率测定进行评估。将四层SIS在37 ° C下浸泡在盐水或林格氏溶液中15分钟，并用薄手术刀轻轻地在贴片的内表面开孔。将贴片铺展固定在图尼卡白蛋白膜上。粘膜缝合的粘膜下移植物，首先在2-3毫米的SIS边缘向内，然后海绵体组织连接到边缘中断可吸收suture.Results：在9例接受使用SIS的尿道扩大术，只有一个有再狭窄，在6个月由于尿道感染。术后18个月时，其他8例患者的尿流率为20-21 mL/s。在并发症方面，6例患者报告有排尿后滴，7例患者报告缺乏晨起35-69 days after surgery.Conclusions：使用SIS是一个安全的程序，但是，需要长期随访，以证实良好的短期结果。
Aim: To present the results from one clinic's experience of using small intestinal submucosa (SIS) in augmentation urethroplasty for management of strictures of the bulbar urethra.Methods: Urethral surgery was performed in nine men with strictures 4-6 cm. All of the patients were evaluated by history, physical examination, retrograde urethrogram, and uroflowmetry. Four layers of SIS were soaked in saline or Ringer's solution for 15 minutes at 37 degrees C, and the inner surface of the patch was gently fenestrated with a thin scalpel. The patch was spread-fixed onto the tunica albuginea. The mucosa was sutured to the submucosal graft first at 2-3 mm inwards from the SIS margins, then the spongiosum tissue was attached to the margins with interrupted absorbable sutures.Results: Of the nine patients who underwent augmentation urethroplasty using SIS, only one had re-stricture at 6 months due to urethral infection. At 18 months after the surgery the uroflowmetry of the other eight patients was 20-21 mL/s. In terms of complications, six patients reported having post-micturition dribbling, and seven patients reported lack of morning erections for 35-69 days after surgery.Conclusions: Using SIS is a safe procedure; however, long-term follow-up is needed to substantiate the good short-term results.