Clinical Characteristics, Management, and Factors Associated with Poor Visual Prognosis of Acute Retinal Necrosis
Clinical Characteristics, Management, and Factors Associated with Poor Visual Prognosis of Acute Retinal Necrosis
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DOI：
10.1080/09273948.2020.1789179
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发表时间：
2020-09-20
影响因子：
3.3
通讯作者：
Mochizuki, Manabu
中科院分区：
文献类型：
--
作者：
Takase, Hiroshi;Goto, Hiroshi;Mochizuki, Manabu
目的：探讨急性视网膜坏死（ARN）的临床特点及影响视力预后的相关因素。研究方法：在日本使用来自149名连续ARN患者的医疗记录的数据进行了一项全国性的多中心回顾性图表审查研究。检查人口统计学、眼部体征、眼内液病毒学检测和治疗。回归分析视力预后不良的相关因素。结果如下：在最初的表现，前房细胞或羊脂肪角膜沉淀物（97%），单侧（93%），黄白色视网膜病变（86%）被识别。在临床过程中，记录了视网膜病变的快速周向扩展（39%），视网膜裂孔或视网膜脱离的发展（55%）和视神经萎缩（43%）。四个变量被确定与不良视力预后相关。结论：本研究确定了ARN的临床特征和与视力预后不良相关的因素。
Purpose: To identify the clinical characteristics of acute retinal necrosis (ARN) and clarify factors associated with poor visual prognosis. Methods: a nationwide multi-center retrospective chart review study was performed in Japan using data from the medical records of 149 consecutive ARN patients. Demographics, ocular signs, virologic testing of intraocular fluids, and treatment were examined. Factors associated with poor visual prognosis were investigated by regression analysis. Results: At initial presentation, anterior chamber cells or mutton-fat keratic precipitates (97%), unilaterality (93%), and yellow-white retinal lesions (86%) were recognized. In the clinical course, rapid circumferential expansion of retinal lesions (39%), development of retinal break or retinal detachment (55%), and optic atrophy (43%) were recorded. Four variables were identified as associated with poor visual prognosis. Conclusions: The present study identified clinical characteristics and factors associated with poor visual prognosis of ARN.