Presence of exacerbating factors of persistent perceptual-postural dizziness in patients with vestibular symptoms at initial presentation.
Presence of exacerbating factors of persistent perceptual-postural dizziness in patients with vestibular symptoms at initial presentation.
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DOI：
10.1002/lio2.735
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发表时间：
2022-04
影响因子：
1.9
通讯作者：
Iwasaki, Shinichi
中科院分区：
文献类型：
--
作者：
Kabaya, Kayoko;Tamai, Hitomi;Okajima, Akina;Minakata, Toshiya;Kondo, Masaki;Nakayama, Meiho;Iwasaki, Shinichi
关键词：
探讨前庭症状患者在前庭症状出现后早期出现持续性知觉体位性头晕（PPPD）的加重因素的存在，并探讨以后发生PPPD的可能预测因素。155例前庭症状患者在发病后90天内出现，并连续纳入本研究。他们填写了新泻PPPD问卷（NPQ），该问卷由12个关于PPPD恶化因素的问题组成。在随访期间比较发生PPPD的患者与未发生PPPD的患者的NPQ评分。155例患者中78例（50.3%）显示NPQ评分阳性（≥27分）。在诊断为心因性头晕和前庭神经炎的患者中，NPQ得分较高。在首次就诊后平均543.3天的随访期间，8名患者（10.3%）发展为PPPD。8例患者中有7例（87.6%）的NPQ评分为阳性，且所有患者在首次就诊时均存在PPPD的所有三种加重因素。发生PPPD的患者NPQ评分（40.6±11.6）明显高于未发生PPPD的患者（26.4±18.3,p < 0.05）。大约一半的前庭症状患者在疾病的早期阶段有加重PPPD的因素。发展为PPPD的患者在发病后的初始阶段可能存在加重因素。证据等级：3。我们发现，后发PPPD的患者在前庭症状出现后的早期，PPPD加重因素的症状明显更严重。
To investigate the presence of exacerbating factors of persistent perceptual‐postural dizziness (PPPD) in patients with vestibular symptoms during the early period after vestibular symptoms onset, and to examine possible predictive factors for developing PPPD later. One hundred and fifty‐five consecutive patients with vestibular symptoms who presented less than 90 days from the onset were included in this study. They filled out the Niigata PPPD Questionnaire (NPQ) that consists of 12 questions on the exacerbating factors of PPPD. The NPQ scores of patients who developed PPPD were compared with those of patients who did not develop PPPD during the follow‐up. Seventy‐eight of the155 patients (50.3%) showed positive NPQ scores (≥27 points). High NPQ scores were found in patients diagnosed with psychogenic dizziness and vestibular neuritis. During the follow up for an average of 543.3 days after the initial presentation, eight patients (10.3%) developed PPPD. Seven of these eight patients (87.6%) showed positive NPQ scores and all of them had all three exacerbating factors of PPPD at their initial presentation. The NPQ scores of the patients who developed PPPD (40.6 ± 11.6) were significantly higher than those of the patients who did not develop PPPD (26.4 ± 18.3; p <.05). Approximately a half of the patients with vestibular symptoms had exacerbating factors of PPPD in the early stages of the disease. Patients who develop PPPD are likely to have its exacerbating factors in the initial stages after presentation. Level of Evidence: 3. We showed that patients who developed PPPD later had significantly more severe symptoms of the exacerbating factors of PPPD during the early period after vestibular symptoms onset.
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影响因子：
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