Updating the beers criteria for potentially inappropriate medication use in older adults - Results of a US consensus panel of experts
Updating the beers criteria for potentially inappropriate medication use in older adults - Results of a US consensus panel of experts
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DOI：
10.1001/archinte.163.22.2716
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发表时间：
2003-12-08
影响因子：
--
通讯作者：
Beers, MH
中科院分区：
文献类型：
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作者：
Fick, DM;Cooper, JW;Beers, MH
背景资料：药物毒性作用和药物相关问题可能对老年人产生深远的医疗和安全后果，并在经济上影响医疗保健系统。这项倡议的目的是修订和更新Beers标准的潜在不适当的药物使用在成年人65岁及以上的美国。方法：本研究采用了修改后的德尔菲法，一套程序和方法，制定一个小组的判断，在一个主题，其中缺乏准确的信息。审查的标准涵盖2种类型的陈述：（1）一般应避免65岁或以上的人使用的药物或药物类别，因为HEV无效或对老年人造成不必要的高风险，并且有更安全的替代品;（2）已知有特定医疗条件的老年人不应使用的药物。这项研究确定了48种单独的药物或药物类别，以避免在老年人和他们的潜在问题和20种疾病/条件和药物，以避免在老年人与这些条件。这些潜在的不适当的药物，66被认为是由小组有不良后果的高severity.Conclusions：这项研究是一个重要的更新以前建立的标准，已被广泛使用和引用。应用Beers标准和其他工具来确定可能不适当的药物使用将继续使供应商能够计划干预措施，以减少与药物有关的费用和总费用，从而尽量减少与药物有关的问题。
Background: Medication toxic effects and drug-related problems can have profound medical and safety consequences for older adults and economically affect the health care system. The purpose of this initiative was to revise and update the Beers criteria for potentially inappropriate medication use in adults 65 years and older in the United States.Methods: This study used a modified Delphi method, a set of procedures and methods for formulating a group judgment for a subject matter in which precise information is lacking. The criteria reviewed covered 2 types of statements: (1) medications or medication classes that should generally be avoided in persons 65 years or older because hev are either ineffective or they pose unnecessarily high risk for older persons and a saferalternative is available and (2) medications that should not be used in older persons known to have specific medical conditions.Results: This study identified 48 individual medications or classes of medications to avoid in older adults and their potential concerns and 20 diseases/conditions and medications to be avoided in older adults with these conditions. Of these potentially inappropriate drugs, 66 were considered by the panel to have adverse outcomes of high severity.Conclusions: This study is an important update of previously established criteria that have been widely used and cited. The application of the Beers criteria and other tools for identifying potentially inappropriate medication use will continue to enable providers to plan interventions for decreasing both drug-related costs and overall costs and thus minimize drug-related problems.